Molecular structure of Ethionamide Sulfoxide, CAS Number: 536-28-7
Ethionamide Sulfoxide (CAS 536-28-7)
Alternate Names:
2-Ethyl-4-pyridinecarbothioamide S-Oxide
Application:
Ethionamide Sulfoxide is major metabolite of Ethionamide
CAS Number:
536-28-7
Molecular Weight:
182.24
Molecular Formula:
C8H10N2OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ethionamide Sulfoxide is the major metabolite of Ethionamide. It is a sulfur-containing compound and serves as an oxidizing agent in a wide array of reactions. Its utility extends to the synthesis of organic compounds, the preparation of pharmaceuticals, and the production of dyes and pigments. It finds application as a catalyst in polymer synthesis and a corrosion inhibitor in fuel cells.
Ethionamide Sulfoxide (CAS 536-28-7) References
- Pharmacokinetic considerations in the treatment of tuberculosis in patients with renal failure. | Launay-Vacher, V., et al. 2005. Clin Pharmacokinet. 44: 221-35. PMID: 15762766
- Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of ethionamide and ethionamide sulfoxide in human plasma: application to a human pharmacokinetic study. | Deshpande, AY., et al. 2011. Biomed Chromatogr. 25: 985-94. PMID: 21268048
- Simultaneous determination of ethionamide and pyrazinamide using poly(l-cysteine) film-modified glassy carbon electrode. | Ferraz, BR., et al. 2016. Talanta. 154: 197-207. PMID: 27154666
- Development of a Physiologically Based Pharmacokinetic Model of Ethionamide in the Pediatric Population by Integrating Flavin-Containing Monooxygenase 3 Maturational Changes Over Time. | Nguyen, PTT., et al. 2018. J Clin Pharmacol. 58: 1347-1360. PMID: 29878384
- Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug-Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3. | Nguyen, PTT., et al. 2019. J Clin Pharmacol. 59: 880-889. PMID: 30690726
- Ethionamide population pharmacokinetics/pharmacodynamics and therapeutic implications in South African adult patients with drug-resistant tuberculosis. | Mugabo, P. and Mulubwa, M. 2021. Br J Clin Pharmacol. 87: 3863-3870. PMID: 33620754
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ethionamide Sulfoxide, 10 mg | sc-211430 | 10 mg | $339.00 |