Ethionamide-d3 (CAS 536-33-4 (unlabeled))

Ethionamide-d3, an isotopically labeled derivative of ethionamide, serves as a valuable tool in biochemical and pharmacological research endeavors. With its deuterium-labeled structure, ethionamide-d3 enables precise tracing and quantification of metabolic pathways and drug metabolism studies. Specifically, it facilitates elucidation of ethionamide′s metabolic fate within biological systems, shedding light on its biotransformation mechanisms, including enzymatic reactions and metabolic pathways involved in its activation, inactivation, and elimination. Moreover, ethionamide-d3 is instrumental in pharmacokinetic investigations, providing insights into its absorption, distribution, metabolism, and excretion properties. By incorporating deuterium into its chemical structure, ethionamide-d3 offers enhanced sensitivity and specificity in analytical techniques such as mass spectrometry, enabling accurate measurement of drug concentrations in biological samples and elucidation of pharmacokinetic profiles. Furthermore, its application extends to drug-drug interaction studies, where it aids in understanding the impact of concomitant medications on ethionamide metabolism and disposition. Overall, ethionamide-d3 serves as a pivotal research tool, facilitating comprehensive investigations into the pharmacokinetics and metabolism of ethionamide, thereby advancing our understanding of its potential and contributing to the development of more efficacious strategies for tuberculosis and related infectious diseases.