Date published: 2026-3-18

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Ethacridine Lactate Monohydrate (CAS 6402-23-9)

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Alternate Names:
6,9-Diamino-2-ethoxyacridine Lactate Monohydrate; Acrinol Lactate Monohydrate
Application:
Ethacridine Lactate Monohydrate is an antiseptic agent that makes an effective abortifacient
CAS Number:
6402-23-9
Purity:
≥98%
Molecular Weight:
361.39
Molecular Formula:
C15H15N3O•C3H6O3•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethacridine Lactate Monohydrate is a derivative of acridine, characterized by its vibrant yellow color and crystalline form. This compound has been extensively used in non-clinical research, particularly in the fields of chemistry and environmental sciences, due to its notable properties as a fluorescent dye and its interactions with nucleic acids. Ethacridine lactate′s primary mechanism of action involves intercalating between the base pairs of DNA, which allows it to serve as a potent tool for studying the structure and function of nucleic acids in various biological and synthetic systems. By inserting itself into the DNA helix, it can effectively disrupt the normal function of DNA, which is a method used to investigate DNA replication, transcription processes, and the binding dynamics of other molecules to DNA. Additionally, the fluorescence properties of ethacridine lactate make it an excellent candidate for use in fluorescence microscopy and other imaging techniques, where it is used to visualize and track DNA and its associated processes within cells. Researchers have also utilized this compound to study the environmental impact of DNA-binding chemicals, assessing how such substances interact with biological systems and persist in the environment, thus providing insights into their ecological and biochemical behavior.


Ethacridine Lactate Monohydrate (CAS 6402-23-9) References

  1. High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis.  |  Mackowiak, B., et al. 2019. Biochem Pharmacol. 168: 224-236. PMID: 31306645
  2. The Influence of Solvent on the Crystal Packing of Ethacridinium Phthalate Solvates.  |  Mirocki, A. and Sikorski, A. 2020. Materials (Basel). 13: PMID: 33182832
  3. Using in silico modelling and FRET-based assays in the discovery of novel FDA-approved drugs as inhibitors of MERS-CoV helicase.  |  Mehyar, N., et al. 2021. SAR QSAR Environ Res. 32: 51-70. PMID: 33401979
  4. Discovery of Zafirlukast as a novel SARS-CoV-2 helicase inhibitor using in silico modelling and a FRET-based assay.  |  Mehyar, N., et al. 2021. SAR QSAR Environ Res. 32: 963-983. PMID: 34818959
  5. Coronaviruses SARS-CoV, MERS-CoV, and SARS-CoV-2 helicase inhibitors: a systematic review of invitro studies.  |  Mehyar, N. 2023. J Virus Erad. 9: 100327. PMID: 37363132
  6. Low-molecular-weight substrate for the lysozyme of T4 bacteriophage.  |  Bieńkowska, K. and Taylor, A. 1979. Eur J Biochem. 96: 581-4. PMID: 380988
  7. Localization of immunoreactive androgen in testicular tissue.  |  Bubenik, GA., et al. 1975. Endocrinology. 96: 63-9. PMID: 45910
  8. Influence of halogen substituent on the self-assembly and crystal packing of multicomponent crystals formed from ethacridine and meta-halobenzoic acids.  |  Mirocki, et al. 2020. Crystals. 10.2: 79.
  9. Efficacy of acriflavin chloride and Melaleuca alternifolia extract against Saprolegnia parasitica infection in Pterophyllum scalare.  |  Lavrinenko, I. V., et al. 2021. Regulatory Mechanisms in Biosystems. 12.3: 472-478.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethacridine Lactate Monohydrate, 25 g

sc-205315
25 g
$71.00

Ethacridine Lactate Monohydrate, 50 g

sc-205315A
50 g
$149.00