Molecular structure of Estrone-d4, CAS Number: 53866-34-5
Estrone-d4 (CAS 53866-34-5)
Alternate Names:
3-Hydroxyestra-1,3,5(10)-trien-17-one-d4
Application:
Estrone-d4 is a labeled 17β-Estradiol metabolite
CAS Number:
53866-34-5
Molecular Weight:
274.39
Molecular Formula:
C18H18D4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Estrone-d4 is a deuterated variant of estrone, a naturally occurring estrogen hormone present in humans and other mammals. This compound holds significant value in laboratory experiments focused on exploring the impacts of estrogens on diverse biological systems. Its widespread utilization in scientific research stems from its stability, low toxicity, and ability to replicate estrogenic effects in biological systems. Researchers have employed Estrone-d4 to investigate the influence of estrogens on cellular growth, development, and differentiation. Moreover, its use has extended to the examination of estrogen-induced effects on gene expression, metabolism, and hormone production.
Estrone-d4 (CAS 53866-34-5) References
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- Elucidation of the dissociation pathways of electro-ionized estrone. | Bouchonnet, S., et al. 2010. Rapid Commun Mass Spectrom. 24: 973-8. PMID: 20209664
- Distribution and bioaccumulation of steroidal and phenolic endocrine disrupting chemicals in wild fish species from Dianchi Lake, China. | Liu, J., et al. 2011. Environ Pollut. 159: 2815-22. PMID: 21645950
- Isolation of estrogen-degrading bacteria from an activated sludge bioreactor treating swine waste, including a strain that converts estrone to β-estradiol. | Isabelle, M., et al. 2011. Can J Microbiol. 57: 559-68. PMID: 21770814
- Biological effects and bioaccumulation of steroidal and phenolic endocrine disrupting chemicals in high-back crucian carp exposed to wastewater treatment plant effluents. | Liu, J., et al. 2012. Environ Pollut. 162: 325-31. PMID: 22243881
- Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study. | Jasuja, GK., et al. 2013. J Gerontol A Biol Sci Med Sci. 68: 733-40. PMID: 23105044
- Development of a liquid chromatography-tandem mass spectrometry procedure for determination of endocrine disrupting compounds in fish from Mediterranean rivers. | Jakimska, A., et al. 2013. J Chromatogr A. 1306: 44-58. PMID: 23890552
- Determination of 13 endocrine disrupting chemicals in sediments by gas chromatography-mass spectrometry using subcritical water extraction coupled with dispersed liquid-liquid microextraction and derivatization. | Yuan, K., et al. 2015. Anal Chim Acta. 866: 41-47. PMID: 25732691
- Comprehensive analyses of genomes, transcriptomes and metabolites of neem tree. | Kuravadi, NA., et al. 2015. PeerJ. 3: e1066. PMID: 26290780
- Genome sequencing of herb Tulsi (Ocimum tenuiflorum) unravels key genes behind its strong medicinal properties. | Upadhyay, AK., et al. 2015. BMC Plant Biol. 15: 212. PMID: 26315624
- Estrogen Transport in Surface Runoff from Agricultural Fields Treated with Two Application Methods of Dairy Manure. | Mina, O., et al. 2016. J Environ Qual. 45: 2007-2015. PMID: 27898780
- Time-series lipidomic analysis of the oleaginous green microalga species Ettlia oleoabundans under nutrient stress. | Matich, EK., et al. 2018. Biotechnol Biofuels. 11: 29. PMID: 29441127
- Determining the presence of chemicals with suspected endocrine activity in drinking water from the Madrid region (Spain) and assessment of their estrogenic, androgenic and thyroidal activities. | Valcárcel, Y., et al. 2018. Chemosphere. 201: 388-398. PMID: 29529566
- Seasonal distribution, risks, and sources of endocrine disrupting chemicals in coastal waters: Will these emerging contaminants pose potential risks in marine environment at continental-scale? | Lu, J., et al. 2020. Chemosphere. 247: 125907. PMID: 31978658
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Estrone-d4, 2.5 mg | sc-207643 | 2.5 mg | $337.00 |