Molecular structure of Estriol, CAS Number: 50-27-1
Estriol (CAS 50-27-1)
Alternate Names:
16α-hydroxy-17β-estradiol; 1,3,5(10)-Estratriene-3,16α,17β-triol
Application:
Estriol is an estradiol metabolite shown to protect against mammary carcinogenisis
CAS Number:
50-27-1
Purity:
>95%
Molecular Weight:
288.38
Molecular Formula:
C18H24O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Estriol acts as an antagonist of the GPR30-dependent pathway. Estriol′s efficacy is due to the interference between estradiol-induced positive cooperative binding and receptor dimerization, as well as the binding of hER complexes to ERE. Estriol is an inhibitor of GPR30.
Estriol (CAS 50-27-1) References
- Effects of estriol on the proliferation and differentiation of human osteoblastic MG-63 cells. | Luo, XH. and Liao, EY. 2003. Endocr Res. 29: 343-51. PMID: 14535635
- Prevention of mammary carcinogenesis by short-term estrogen and progestin treatments. | Rajkumar, L., et al. 2004. Breast Cancer Res. 6: R31-7. PMID: 14680498
- Efficacy of low-dose intravaginal estriol on urogenital aging in postmenopausal women. | Dessole, S., et al. 2004. Menopause. 11: 49-56. PMID: 14716182
- Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol. | Sneitz, N., et al. 2013. Drug Metab Dispos. 41: 582-91. PMID: 23288867
- Estriol and its conjugates in late pregnancy determined by extraction with Carbopack B and liquid chromatography with fluorometric detection. | Andreolini, F., et al. 1985. Clin Chem. 31: 1698-702. PMID: 2994907
- A simple radioimmunoassay for estriol 3-sulfate in pregnancy plasma without deconjugation. | Tanaka, T., et al. 1985. Steroids. 46: 649-57. PMID: 3837408
- Estriol radioimmunoassay in plasma and urine. | Castro, A., et al. 1985. Res Commun Chem Pathol Pharmacol. 50: 291-9. PMID: 4081318
- [Value of the rapid determination of estriol and creatinine during course of the last trimester of pregnancy on the 1st morning urine]. | Goldberg, S., et al. 1972. Rev Fr Gynecol Obstet. 67: 127-9. PMID: 5053625
- Preliminary isolation of urinary placental estriol before gas or liquid chromatography. | Andreolini, F., et al. 1983. Clin Chem. 29: 2076-8. PMID: 6640903
- Salivary estriol concentrations during normal pregnancies, and a comparison with plasma estriol. | Evans, JJ., et al. 1984. Clin Chem. 30: 120-1. PMID: 6690116
- Uterine vascular effects of estetrol in nonpregnant ewes. | Levine, MG., et al. 1984. Am J Obstet Gynecol. 148: 735-8. PMID: 6702941
- Biological responses and histological studies of estriol and estriol sulfate in fetal and newborn uteri of guinea pig. | Pasqualini, JR. and Nguyen, BL. 1984. J Steroid Biochem. 20: 1047-55. PMID: 6727350
- Homogeneous enzyme immunoassay of estriol in picogram amounts. | Ghosh, M., et al. 1983. Clin Chim Acta. 128: 223-31. PMID: 6851138
- Two-hour Sephadex column method for assay of unconjugated estriol in serum. | Haigh, WG., et al. 1980. Clin Chem. 26: 309-12. PMID: 7353284
- Oestrogen in human pregnancy faeces. | Adlercreutz, H. and Martin, F. 1976. Acta Endocrinol (Copenh). 83: 410-9. PMID: 989669
Inhibitor of:
GPR30, and Mesotrypsinogen.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Estriol, 100 mg | sc-205682 | 100 mg | $21.00 | |||
Estriol, 500 mg | sc-205682A | 500 mg | $65.00 |