Molecular structure of Erysolin, CAS Number: 504-84-7
Erysolin (CAS 504-84-7)
See product citations (2)
Alternate Names:
1-Isothiocyanato-4-(methylsulphonyl)butane
Application:
Erysolin is a chemical shown to increase the amount of daunomycin and vinblastine in PANC-1 cells
CAS Number:
504-84-7
Purity:
≥97%
Molecular Weight:
193.29
Molecular Formula:
C6H11NO2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Erysolin has been shown to increase the amount of daunomycin and vinblastine in PANC-1 cells. Daunomycin and vinblastine is known to act as substrates for enzymes that assisted in drug-resistance of human cancer cell lines.
Erysolin (CAS 504-84-7) References
- Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine. | Tseng, E., et al. 2002. Pharm Res. 19: 1509-15. PMID: 12425469
- Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (HepG2) cells towards benzo(a)pyrene and their mode of action. | Lamy, E., et al. 2008. Food Chem Toxicol. 46: 2415-21. PMID: 18479797
- Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism. | Doudican, NA., et al. 2010. Leuk Res. 34: 229-34. PMID: 19540589
- D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. | Kim, SH. and Singh, SV. 2009. Mol Cancer Ther. 8: 1946-54. PMID: 19584240
- Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. | Kim, MJ., et al. 2010. Anticancer Res. 30: 3611-9. PMID: 20944144
- Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity. | Kawasumi, M., et al. 2014. Cancer Res. 74: 7534-45. PMID: 25336189
- In vivo study of erysolin metabolic profile by ultra high performance liquid chromatography coupleded to Fourier transform ion cyclotron resonance mass spectrometry. | Li, B., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1072: 173-181. PMID: 29175697
- Structures of isothiocyanates attributed to reactive oxygen species generation and microtubule depolymerization in HepG2 cells. | Pocasap, P., et al. 2018. Biomed Pharmacother. 101: 698-709. PMID: 29522950
- Induction of the Stringent Response Underlies the Antimicrobial Action of Aliphatic Isothiocyanates. | Nowicki, D., et al. 2020. Front Microbiol. 11: 591802. PMID: 33584562
- Synthesis and antitumor activity of erysolin and its metabolites. | Li, BL., et al. 2023. J Asian Nat Prod Res. 25: 369-378. PMID: 35763370
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Erysolin, 25 mg | sc-205679 | 25 mg | $223.00 | |||
Erysolin, 50 mg | sc-205679A | 50 mg | $391.00 |