Date published: 2025-9-5

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Eriodictyol (CAS 4049-38-1)

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Alternate Names:
3′,4′,5,7-Tetrahydroxyflavanone
CAS Number:
4049-38-1
Purity:
≥95%
Molecular Weight:
288.25
Molecular Formula:
C15H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Eriodictyol, a naturally occurring flavonoid and polyphenol, possesses both antioxidant and anti-inflammatory properties. It can be found in various plants, including citrus fruits, as well as herbs like thyme, oregano, and rosemary. Furthermore, eriodictyol has demonstrated the capacity to induce apoptosis in cancer cells and reduce the production of pro-inflammatory cytokines. Its effects include diminishing the production of reactive oxygen species, inhibiting inflammation-related enzymes, promoting cancer cell apoptosis, and improving cognitive function.


Eriodictyol (CAS 4049-38-1) References

  1. The Nrf2/HO-1 Axis as Targets for Flavanones: Neuroprotection by Pinocembrin, Naringenin, and Eriodictyol.  |  Habtemariam, S. 2019. Oxid Med Cell Longev. 2019: 4724920. PMID: 31814878
  2. The pharmacological and biological roles of eriodictyol.  |  Islam, A., et al. 2020. Arch Pharm Res. 43: 582-592. PMID: 32594426
  3. Pharmacological Activity of Eriodictyol: The Major Natural Polyphenolic Flavanone.  |  Deng, Z., et al. 2020. Evid Based Complement Alternat Med. 2020: 6681352. PMID: 33414838
  4. Eriodictyol protects skin cells from UVA irradiation-induced photodamage by inhibition of the MAPK signaling pathway.  |  Nisar, MF., et al. 2022. J Photochem Photobiol B. 226: 112350. PMID: 34785489
  5. Effect of Eriodictyol on Retinoblastoma via the PI3K/Akt Pathway.  |  Wen, S., et al. 2021. J Healthc Eng. 2021: 6091585. PMID: 34804455
  6. Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.  |  Li, L., et al. 2022. Mol Med. 28: 11. PMID: 35093024
  7. Eriodictyol suppresses the malignant progression of colorectal cancer by downregulating tissue specific transplantation antigen P35B (TSTA3) expression to restrain fucosylation.  |  Huang, H., et al. 2022. Bioengineered. 13: 5551-5563. PMID: 35184647
  8. Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis.  |  Debnath, S., et al. 2022. Transl Oncol. 21: 101433. PMID: 35462210
  9. Biosynthesis of eriodictyol from tyrosine by Corynebacterium glutamicum.  |  Wu, X., et al. 2022. Microb Cell Fact. 21: 86. PMID: 35568867
  10. Bioproduction of eriodictyol by Escherichia coli engineered co-culture.  |  Thuan, NH., et al. 2022. World J Microbiol Biotechnol. 38: 112. PMID: 35570219
  11. Eriodictyol inhibits breast carcinogenesis by targeting circ_0007503 and repressing PI3K/Akt pathway.  |  He, J., et al. 2022. Phytomedicine. 102: 154159. PMID: 35580441
  12. Eriodictyol Attenuates H2O2-Induced Oxidative Damage in Human Dermal Fibroblasts through Enhanced Capacity of Antioxidant Machinery.  |  Buranasudja, V., et al. 2022. Nutrients. 14: PMID: 35745283
  13. Eriodictyol Attenuates Cholangiocarcinoma Malignancy by Regulating HMOX1 Expression: An In Vitro Study.  |  Lee, J., et al. 2022. Anticancer Res. 42: 3789-3798. PMID: 35896263
  14. Eriodictyol Suppresses Gastric Cancer Cells via Inhibition of PI3K/AKT Pathway.  |  Shan, H., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 36558929

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Eriodictyol, 50 mg

sc-263117
50 mg
$490.00