ERI-1 Antibody (C-8): sc-137099
- ERI-1 Antibody (C-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 161-295 mapping within an internal region of ERI-1 of human origin
- recommended for detection of ERI-1 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-137099 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ERI-1 Antibody (C-8) for WB applications. These reagents are now offered in bundles with ERI-1 Antibody (C-8) (see ordering information below).
QUICK LINKS
SEE ALSO...
ERI-1 Antibody (C-8) is a mouse monoclonal IgG1 antibody that detects ERI-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ERI-1, also known as Protein 3′hExo, plays a crucial role in RNA interference regulation by degrading histone mRNA after replication, which is essential for maintaining proper gene expression and cellular function. ERI-1 exhibits a high affinity for the stem-loop structure of replication-dependent histone pre-mRNAs, specifically requiring the 5′-ACCCA-3′ sequence found within this structure. The interaction between ERI-1 and a stem-loop binding protein (SLBP) is particularly significant, as they target opposite faces of a highly conserved stem-loop RNA scaffold, facilitating precise degradation of histone mRNA. Anti-ERI-1 antibody (C-8) enables researchers to gain valuable insights into RNA regulation mechanisms and intricate processes governing gene expression, making this tool indispensable for studies in molecular biology and genetics.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ERI-1 Antibody (C-8) | sc-137099 | 200 µg/ml | $322.00 | |||
ERI-1 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-537400 | 200 µg Ab; 10 µg BP | $361.00 | |||
ERI-1 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-534654 | 200 µg Ab; 40 µg BP | $361.00 | |||
ERI-1 Antibody (C-8) X | sc-137099 X | 200 µg/0.1 ml | $322.00 |