Date published: 2025-9-5

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ErbB3/HER3 抗体 (RTJ.2): sc-415

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说明书
  • ErbB3/HER3抗体(RTJ.2)是小鼠单克隆IgG1 κ, 在61篇文献中引用,规格为200 µg/ml
  • 在human起源的ErbB-3的细胞质域内的表位图谱
  • 抗-ErbB3/HER3 抗体 (RTJ.2) 推荐用于 WB, IP, IF, IHC(P) 和 FCM,检测mouse, rat 和human 来源的 ErbB-3
  • 抗ErbB3/HER3抗体(RTJ.2)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取ErbB3/HER3 (RTJ.2): sc-415免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 ErbB3/HER3 抗体 (RTJ.2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与ErbB3/HER3 抗体 (RTJ.2) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

ErbB-3抗体(RTJ.2)是一种小鼠单克隆IgG2b kappa轻链抗体,针对人ErbB-3的细胞质结构域,ErbB-3是ErbB受体酪氨酸激酶家族的重要成员。ErbB-3小鼠单克隆抗体(RTJ.2)可识别细胞质区域内的表位,并表现出广泛的物种交叉反应性,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和流式细胞术(FCM)检测小鼠、大鼠、牛、猪和人类样本中的ErbB-3。抗ErbB-3单克隆抗体(RTJ.2)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和各种Alexa Fluor®结合物,可满足各种实验需求。ErbB-3,也称为FERLK、HER3、LCCS2、MDA-BF-1、VSCN1、erbB3-S和ERBB3,在细胞膜上保持精确的定位,ErbB-3在细胞膜上协调复杂的细胞信号网络。这种战略定位使ErbB-3能够对如heregulin等配体作出反应,并与其他家族成员(尤其是ErbB-2(HER2))形成同源二聚体或异源二聚体。这些二聚化事件会触发关键的下游信号级联,特别是磷脂酰肌醇3激酶(PI3K)通路,该通路可调节细胞生长、存活和分化。ErbB-3在癌症生物学中的临床意义尤为明显,ErbB-3在包括人类乳腺肿瘤在内的多种癌症中经常出现过度表达。这种失调会加剧致癌过程,并导致治疗抵抗。ErbB-3(RTJ.2)抗体通过这些不同的细胞功能,为研究人员提供了研究癌症发展机制和推进靶向治疗策略的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

ErbB3/HER3 抗体 (RTJ.2)

sc-415
200 µg/ml
$316.00

ErbB3/HER3 (RTJ.2): m-IgG Fc BP-HRP 套装

sc-526456
200 µg Ab; 10 µg BP
$354.00

ErbB3/HER3 (RTJ.2): m-IgG1 BP-HRP 套装

sc-531829
200 µg Ab; 20 µg BP
$354.00

ErbB3/HER3 抗体 (RTJ.2) AC

sc-415 AC
500 µg/ml, 25% agarose
$416.00

ErbB3/HER3 抗体 (RTJ.2) HRP

sc-415 HRP
200 µg/ml
$316.00

ErbB3/HER3 抗体 (RTJ.2) FITC

sc-415 FITC
200 µg/ml
$330.00

ErbB3/HER3 抗体 (RTJ.2) PE

sc-415 PE
200 µg/ml
$343.00

ErbB3/HER3 抗体 (RTJ.2) Alexa Fluor® 488

sc-415 AF488
200 µg/ml
$357.00

ErbB3/HER3 抗体 (RTJ.2) Alexa Fluor® 546

sc-415 AF546
200 µg/ml
$357.00

ErbB3/HER3 抗体 (RTJ.2) Alexa Fluor® 594

sc-415 AF594
200 µg/ml
$357.00

ErbB3/HER3 抗体 (RTJ.2) Alexa Fluor® 647

sc-415 AF647
200 µg/ml
$357.00

ErbB3/HER3 抗体 (RTJ.2) Alexa Fluor® 680

sc-415 AF680
200 µg/ml
$357.00

ErbB3/HER3 抗体 (RTJ.2) Alexa Fluor® 790

sc-415 AF790
200 µg/ml
$357.00

Can ErbB-3 (RTJ.2): sc-415 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: cjMara
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, ErbB-3 (RTJ.2): sc-415 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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ErbB3/HER3 抗体 (RTJ.2) is rated 5.0 out of 5 by 6.
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