Molecular structure of Eprinomectin, CAS Number: 123997-26-2
Eprinomectin (CAS 123997-26-2)
Alternate Names:
(4′R)-4″-(Acetylamino)-4″-deoxy-avermectin B1; Eprinex
Application:
Eprinomectin is a mixture of Eprinomectin B1a and B1b showing anti-anthelintic activity
CAS Number:
123997-26-2
Molecular Weight:
914.13
Molecular Formula:
C50H75NO14
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
The compound Eprinomectin consists of two components: eprinomectin B1a and eprinomectin B1b. In terms of production, it is obtained through fermentation by soil-dwelling Streptomyces. Eprinomectin falls under the category of avermectins, which are macrocyclic lactones. Eprinomectin also serves as an endectocide, acting as a semi-synthetic GABA signaling potentiator.
Eprinomectin (CAS 123997-26-2) References
- Eprinomectin from a sustained release formulation adversely affected dung breeding insects. | Nieman, CC., et al. 2018. PLoS One. 13: e0201074. PMID: 30080892
- Review of the Eprinomectin effective doses required for dairy goats: Where do we go from here? | Rostang, A., et al. 2020. Vet Parasitol. 277: 108992. PMID: 31835054
- Injectable eprinomectin for cattle: Tick efficacy and pharmacokinetics. | do Nascimento, CG., et al. 2020. J Vet Pharmacol Ther. 43: 171-178. PMID: 32030782
- Eprinomectin, a novel semi-synthetic macrocylic lactone is cytotoxic to PC3 metastatic prostate cancer cells via inducing apoptosis. | Samy, ALPA., et al. 2020. Toxicol Appl Pharmacol. 401: 115071. PMID: 32454055
- NexGard® Combo (esafoxolaner, eprinomectin, praziquantel), a new endectoparasiticide spot-on formulation for cats. | Beugnet, F. 2021. Parasite. 28: E1. PMID: 33812448
- Pour-on administration of eprinomectin to lactating dairy goats: Pharmacokinetics and anthelmintic efficacy. | Hamel, D., et al. 2021. J Vet Pharmacol Ther. 44: 952-960. PMID: 34542908
- Preparation of Eprinomectin Nanoemulsions and Determination of Their Pharmacokinetics and Pharmacodynamics in Dairy Cows. | Gang, Q. and Yapei, R. 2022. J Biomed Nanotechnol. 18: 512-526. PMID: 35484758
- Eprinomectin 5% w/v extended-release injection for the treatment of larval and/or adult Bunostomum phlebotomum, Haemonchus contortus, H. placei, Nematodirus helvetianus, Oesophagostomum radiatum, and Trichostrongylus colubriformis infections in cattle. | Hamel, D., et al. 2022. Parasitol Res. 121: 2173-2178. PMID: 35503138
- Eprinomectin and Moxidectin Resistance of Trichostrongyloids on a Goat Farm in Austria. | Hinney, B., et al. 2022. Pathogens. 11: PMID: 35631019
- Effects of flumethrin and eprinomectin in naturally infected mice with Myocoptes musculinus. | Aktas, S., et al. 2022. Exp Parasitol. 239: 108307. PMID: 35709888
- Environmentally realistic concentrations of eprinomectin induce phytotoxic and genotoxic effects in Allium cepa. | de Souza, RB., et al. 2022. Environ Sci Pollut Res Int. 29: 80983-80993. PMID: 35727508
- Simultaneous Determination of Esafoxolaner, Eprinomectin, Praziquantel, BHT and Their Related Substances in a Topical Finished Product by a Single Reversed-Phase High-Performance Liquid Chromatography Method. | Chopra, S., et al. 2022. J Chromatogr Sci.. PMID: 36151056
- Efficacy of eprinomectin topical solution and eprinomectin extended-release injection treatments against developing larval and adult Chabertia ovina and Oesophagostomum venulosum - two less common cattle nematode parasites. | Rehbein, S., et al. 2022. Vet Parasitol. 312: 109837. PMID: 36335833
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Eprinomectin, 100 mg | sc-204740 | 100 mg | $154.00 | |||
Eprinomectin, 500 mg | sc-204740B | 500 mg | $321.00 |