Molecular structure of Epirubicin Hydrochloride, CAS Number: 56390-09-1
Epirubicin Hydrochloride (CAS 56390-09-1)
See product citations (2)
Alternate Names:
4′-Epidoxorubicin, HCl
Application:
Epirubicin Hydrochloride is a cell-permeable Topo II inhibitor
CAS Number:
56390-09-1
Purity:
≥98%
Molecular Weight:
580.00
Molecular Formula:
C27H29NO11•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Epirubicin Hydrochloride is a cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin (sc-280681) that exhibits reduced cardiotoxicity. Epirubicin Hydrochloride′s antitumor actions are mediated by targeting and inhibiting Topo II (topoisomerase II).
Epirubicin Hydrochloride (CAS 56390-09-1) References
- The effects of epirubicin hydrochloride (EPI) plus pretreatment of medroxyprogesterone acetate (MPA) on FM3A breast cancer cells transplanted in female C3H/He mice. | Yuyama, Y., et al. 2003. In Vivo. 17: 251-4. PMID: 12929575
- Epirubicin-encapsulated long-circulating thermosensitive liposome improves pharmacokinetics and antitumor therapeutic efficacy in animals. | Wu, Y., et al. 2011. J Liposome Res. 21: 221-8. PMID: 20929434
- Experiment on enhancing antitumor effect of intravenous epirubicin hydrochloride by acoustic cavitation in situ combined with phospholipid-based microbubbles. | Lu, CT., et al. 2011. Cancer Chemother Pharmacol. 68: 343-8. PMID: 20978763
- Adsorption behavior of epirubicin hydrochloride on carboxylated carbon nanotubes. | Chen, Z., et al. 2011. Int J Pharm. 405: 153-61. PMID: 21145959
- [Pharmacokinetics of epirubicin hydrochloride long-circulating thermosensitive liposomes in rat plasma]. | Wu, Y., et al. 2010. Yao Xue Xue Bao. 45: 365-70. PMID: 21351514
- Surface functionalized mesoporous silica nanoparticles as an effective carrier for epirubicin delivery to cancer cells. | Hanafi-Bojd, MY., et al. 2015. Eur J Pharm Biopharm. 89: 248-58. PMID: 25511563
- Synthesis and application of thiol-functionalized magnetic nanoparticles for studying interactions of epirubicin hydrochloride with bovine serum albumin by fluorescence spectrometry. | Xiong, H., et al. 2017. Luminescence. 32: 142-148. PMID: 27193868
- Effect of medroxyprogesterone acetate, alone or in combination with epirubicin hydrochloride, on the growth of the Dunning R3327H prostatic adenocarcinoma. | Landström, M., et al. 1987. Eur Urol. 13: 203-6. PMID: 2956111
- Interaction of Anticancer Drugs with Human Organic Anion Transporter hOAT4. | Liu, C., et al. 2019. J Oncol. 2019: 1951786. PMID: 30941173
- Hierarchically Nanostructured Fe₃O₄/C Composite as a Promising Magnetic Targeted Drug Nanocarrier. | Wang, DY., et al. 2019. J Nanosci Nanotechnol. 19: 7532-7538. PMID: 31196257
- In vitro compatibility and stability of admixtures containing etoposide, epirubicin hydrochloride and vindesine sulphate in a single infusion bag. | Li, J., et al. 2019. J Clin Pharm Ther. 44: 875-882. PMID: 31529525
- Thermal Reversibility and Structural Stability in Lysozyme Induced by Epirubicin Hydrochloride. | Khamari, L., et al. 2021. Langmuir. 37: 3456-3466. PMID: 33703900
- Preferential Binding of Epirubicin Hydrochloride with Single Nucleotide Mismatched DNA and Subsequent Sequestration by a Mixed Micelle. | Khamari, L., et al. 2021. J Phys Chem B. 125: 11660-11672. PMID: 34652157
Inhibitor of:
Topo II.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Epirubicin Hydrochloride, 5 mg | sc-203041 | 5 mg | $153.00 | |||
Epirubicin Hydrochloride, 25 mg | sc-203041A | 25 mg | $292.00 | |||
Epirubicin Hydrochloride, 100 mg | sc-203041B | 100 mg | $550.00 |