Date published: 2026-3-7

1-800-457-3801

SCBT Portrait Logo
Seach Input

(−)Epigallocatechin (CAS 970-74-1)

0.0(0)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
(−)-EGC; epi-Gallocatechin; NSC 674039
Application:
(−)Epigallocatechin is a natural product from green tea shown to inhibit DNA polymerase
CAS Number:
970-74-1
Purity:
≥98%
Molecular Weight:
306.27
Molecular Formula:
C15H14O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

(−)Epigallocatechin is a polyphenolic compound that functions as an antioxidant in experimental applications. It exerts its mechanism of action by scavenging free radicals and inhibiting oxidative stress at the molecular level. (−)Epigallocatechin has the ability to interact with reactive oxygen species, preventing cellular damage and maintaining cellular homeostasis. (−)Epigallocatechin also demonstrates the capacity to modulate various signaling pathways, influencing gene expression and cellular responses. Its role in experimental applications involves regulating redox balance and protecting cells from oxidative damage. (−)Epigallocatechin may have an impact on certain enzymes and proteins involved in oxidative stress pathways, contributing to its antioxidant properties. (−)Epigallocatechin plays a functional role in experimental research by serving as an antioxidant and modulating cellular responses to oxidative stress.


(−)Epigallocatechin (CAS 970-74-1) References

  1. Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media.  |  Long, LH., et al. 2000. Biochem Biophys Res Commun. 273: 50-3. PMID: 10873562
  2. (-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts.  |  Vergote, D., et al. 2002. Breast Cancer Res Treat. 76: 195-201. PMID: 12462380
  3. Metabolism of (-)-epigallocatechin gallate by rat intestinal flora.  |  Takagaki, A. and Nanjo, F. 2010. J Agric Food Chem. 58: 1313-21. PMID: 20043675
  4. Analysis of binding interaction between (-)-epigallocatechin (EGC) and β-lactoglobulin by multi-spectroscopic method.  |  Wu, X., et al. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 82: 164-8. PMID: 21820944
  5. Enantioselective total syntheses of (+)-gallocatechin, (-)-epigallocatechin, and 8-C-ascorbyl-(-)-epigallocatechin.  |  Lin, G., et al. 2013. Chem Asian J. 8: 700-4. PMID: 23362126
  6. Molecular interactions between (-)-epigallocatechin gallate analogs and pancreatic lipase.  |  Wang, S., et al. 2014. PLoS One. 9: e111143. PMID: 25365042
  7. Biotransformation of (-)-epigallocatechin and (-)-gallocatechin by intestinal bacteria involved in isoflavone metabolism.  |  Takagaki, A. and Nanjo, F. 2015. Biol Pharm Bull. 38: 325-30. PMID: 25747993
  8. Efficacy of Topical Treatment with (-)-Epigallocatechin Gallate, A Green Tea Catechin, in Mice with Cutaneous Leishmaniasis.  |  Sosa, AM., et al. 2020. Molecules. 25: PMID: 32290128
  9. Influence of sodium tripolyphosphate coupled with (-)-epigallocatechin on the in vitro digestibility and emulsion gel properties of myofibrillar protein under oxidative stress.  |  Chen, J., et al. 2020. Food Funct. 11: 6407-6421. PMID: 32613953
  10. Green tea extract-biomembrane interaction study: The role of its two major components, (-)-epigallocatechin gallate and (-)-epigallocatechin.  |  Andrade, S., et al. 2021. Biochim Biophys Acta Biomembr. 1863: 183476. PMID: 32946887
  11. Inhibition of Aβ aggregates in Alzheimer's disease by epigallocatechin and epicatechin-3-gallate from green tea.  |  Chen, T., et al. 2020. Bioorg Chem. 105: 104382. PMID: 33137558
  12. Structure, stability and antioxidant activity of dialdehyde starch grafted with epicatechin, epicatechin gallate, epigallocatechin and epigallocatechin gallate.  |  Yong, H., et al. 2022. J Sci Food Agric. 102: 6373-6386. PMID: 35535559
  13. Caseinate-reinforced pectin hydrogels: Efficient encapsulation, desirable release, and chemical stabilization of (-)-epigallocatechin.  |  Yang, M., et al. 2023. Int J Biol Macromol. 230: 123298. PMID: 36646343

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(−)Epigallocatechin, 1 mg

sc-205673
1 mg
$65.00

(−)Epigallocatechin, 5 mg

sc-205673A
5 mg
$204.00