Date published: 2025-10-2

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Epibrassinolide (CAS 78821-43-9)

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Application:
Epibrassinolide is a steroidal lactone
CAS Number:
78821-43-9
Molecular Weight:
480.68
Molecular Formula:
C28H48O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Epibrassinolide is a plant growth stimulant. it is a plant hormone derived from the brassinosteroid family. Studies show that Epibrassinolide possesses the ability to enhance cellular division and elongation, stimulate root growth and development, and facilitate the processes of flowering and seed germination. Moreover, Epibrassinolide exhibits protective properties, guarding plants against adverse environmental conditions such as drought and salinity.


Epibrassinolide (CAS 78821-43-9) References

  1. Epibrassinolide induces changes in indole-3-acetic acid, abscisic acid and polyamine concentrations and enhances antioxidant potential of radish seedlings under copper stress.  |  Choudhary, SP., et al. 2010. Physiol Plant. 140: 280-96. PMID: 20681975
  2. Epibrassinolide ameliorates Cr (VI) stress via influencing the levels of indole-3-acetic acid, abscisic acid, polyamines and antioxidant system of radish seedlings.  |  Choudhary, SP., et al. 2011. Chemosphere. 84: 592-600. PMID: 21561640
  3. Activation of polyamine catabolic enzymes involved in diverse responses against epibrassinolide-induced apoptosis in LNCaP and DU145 prostate cancer cell lines.  |  Obakan, P., et al. 2014. Amino Acids. 46: 553-64. PMID: 23963538
  4. Epibrassinolide-induced apoptosis regardless of p53 expression via activating polyamine catabolic machinery, a common target for androgen sensitive and insensitive prostate cancer cells.  |  Obakan, P., et al. 2014. Prostate. 74: 1622-33. PMID: 25214240
  5. Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells.  |  Coskun, D., et al. 2015. Exp Cell Res. 338: 10-21. PMID: 26318418
  6. SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells.  |  Obakan, P., et al. 2015. PLoS One. 10: e0135788. PMID: 26353013
  7. Calreticulin is a fine tuning molecule in epibrassinolide-induced apoptosis through activating endoplasmic reticulum stress in colon cancer cells.  |  Obakan-Yerlikaya, P., et al. 2017. Mol Carcinog. 56: 1603-1619. PMID: 28112451
  8. Epibrassinolide-induced autophagy occurs in an Atg5-independent manner due to endoplasmic stress induction in MEF cells.  |  Adacan, K., et al. 2020. Amino Acids. 52: 871-891. PMID: 32449072
  9. Epibrassinolide activates AKT to trigger autophagy with polyamine metabolism in SW480 and DLD-1 colon cancer cell lines.  |  Adacan, K. and Obakan Yerlİkaya, P. 2020. Turk J Biol. 44: 417-426. PMID: 33402868
  10. Epibrassinolide prevents tau hyperphosphorylation via GSK3β inhibition in vitro and improves Caenorhabditis elegans lifespan and motor deficits in combination with roscovitine.  |  Obakan Yerlikaya, P., et al. 2021. Amino Acids. 53: 1373-1389. PMID: 34386848
  11. Epibrassinolide improves the growth performance of Sedum lineare upon Zn stress through boosting antioxidative capacities.  |  Zhang, Y. and Liao, H. 2021. PLoS One. 16: e0257172. PMID: 34492083
  12. Epibrassinolide enhanced chilling tolerance of postharvest banana fruit by regulating energy status and pyridine nucleotide homeostasis.  |  Li, D., et al. 2022. Food Chem. 382: 132273. PMID: 35152013
  13. OsSLA1 functions in leaf angle regulation by enhancing the interaction between OsBRI1 and OsBAK1 in rice.  |  Song, Y., et al. 2022. Plant J. 110: 1111-1127. PMID: 35275421
  14. Epibrassinolide impaired colon tumor progression and induced autophagy in SCID mouse xenograft model via acting on cell cycle progression without affecting endoplasmic reticulum stress observed in vitro.  |  Obakan Yerlikaya, P., et al. 2023. Int J Biochem Cell Biol. 155: 106360. PMID: 36587800

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Epibrassinolide, 10 mg

sc-211419
10 mg
$353.00