Molecular structure of Eperisone Hydrochloride, CAS Number: 56839-43-1
Eperisone Hydrochloride (CAS 56839-43-1)
See product citations (3)
Alternate Names:
1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride
Application:
Eperisone Hydrochloride is a spasmolytic agent related structurally to Tolperisone
CAS Number:
56839-43-1
Purity:
≥98%
Molecular Weight:
295.85
Molecular Formula:
C17H25NO•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Eperisone hydrochloride is a small molecule. Its small size allows it to permeate cell membranes, after which it can interact with its target to exert its mechanism of action. Eperisone hydrochloride′s main mechanism of action is targeting Voltage-Dependent Calcium Channels (VDCCs). VDCCs can be found in excitable cells. Excitable cells are cells that can create an electric current. Excitable cells include neurons, muscle cells, and glial cells. Eperisone hydrochloride has been found to bind to human serum albumin (HSA) in Sudlow Site I of HSA (subdomain IIA). This bonding interaction is spontaneous. The complex forms mostly due to hydrophobic interactions and hydrogen bonds.
Eperisone Hydrochloride (CAS 56839-43-1) References
- Transdermal eperisone elicits more potent and longer-lasting muscle relaxation than oral eperisone. | Yang, SI., et al. 2004. Pharmacology. 71: 150-6. PMID: 15161997
- [Pharmacokinetics and bioequivalence of eperisone hydrochloride tablet in healthy subjects]. | Wei, X., et al. 2004. Yao Xue Xue Bao. 39: 309-11. PMID: 15303666
- The use of HPLC/MS, GC/MS, NMR, UV and IR to identify a degradation product of eperisone hydrochloride in the tablets. | Ding, L., et al. 2008. J Pharm Biomed Anal. 46: 282-7. PMID: 18023316
- Human pharmacokinetics of the muscle relaxant, eperisone hydrochloride by liquid chromatography-electrospray tandem mass spectrometry. | Melilli, B., et al. 2011. Eur J Drug Metab Pharmacokinet. 36: 71-8. PMID: 21448778
- Pharmacokinetic interactions between eperisone hydrochloride and aceclofenac: a randomized, open-label, crossover study of healthy Korean men. | Kim, MJ., et al. 2013. Clin Ther. 35: 1528-35. PMID: 24050970
- Serum concentration of eperisone hydrochloride correlates with QT interval. | Yamagiwa, T., et al. 2014. Am J Emerg Med. 32: 75-7. PMID: 24135462
- Simultaneous determination of eperisone hydrochloride and paracetamol in mouse plasma by high performance liquid chromatography-photodiode array detector. | Locatelli, M., et al. 2015. J Chromatogr A. 1388: 79-86. PMID: 25704771
- A case of eperisone hydrochloride-induced anaphylaxis: A true type I reaction? | Miki, Y., et al. 2017. Allergol Int. 66: 152-153. PMID: 27544644
- Pharmacokinetic Interactions Between Pelubiprofen and Eperisone Hydrochloride: A Randomized, Open-label, Crossover Study of Healthy Korean Men. | Ryu, JH., et al. 2017. Clin Ther. 39: 138-149. PMID: 27989618
- Biophysical Study on the Interaction between Eperisone Hydrochloride and Human Serum Albumin Using Spectroscopic, Calorimetric, and Molecular Docking Analyses. | Rabbani, G., et al. 2017. Mol Pharm. 14: 1656-1665. PMID: 28380300
- Failure Mode Critical Effect Analysis and Design of Experiment-Based Robust Chromatographic Method for Simultaneous Estimation Lornoxicam and Eperisone Hydrochloride. | Prajapati, P., et al. 2020. J Chromatogr Sci. 58: 929-939. PMID: 32887996
- Effects of Eperisone Hydrochloride and Non-Steroid Anti-Inflammatory Drugs (NSAIDs) for Acute Non-Specific Back Pain with Muscle Spasm: A Prospective, Open-Label Study. | Pinzon, RT., et al. 2020. Drug Healthc Patient Saf. 12: 221-228. PMID: 33235514
- Long-lasting muscle relaxant activity of eperisone hydrochloride after percutaneous administration in rats. | Matsunaga, M., et al. 1997. Jpn J Pharmacol. 73: 215-20. PMID: 9127816
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Eperisone Hydrochloride, 100 mg | sc-211415 | 100 mg | $150.00 | |||
Eperisone Hydrochloride, 2 g | sc-211415A | 2 g | $265.00 | |||
Eperisone Hydrochloride, 5 g | sc-211415B | 5 g | $398.00 | |||
Eperisone Hydrochloride, 10 g | sc-211415C | 10 g | $653.00 | |||
Eperisone Hydrochloride, 25 g | sc-211415D | 25 g | $1173.00 |