Eosin Y Disodium Trihydrate (CAS 17372-87-1)
See product citations (1)
QUICK LINKS
Protein methyltransferase inhibitor AMI-5 is a compound that targets and inhibits the activity of protein methyltransferases. It functions by binding to the active site of the enzyme, preventing the transfer of methyl groups to target proteins. This inhibition disrupts the normal methylation process, leading to alterations in protein function and downstream signaling pathways. AMI-5 acts as a competitive inhibitor, effectively competing with the substrate for binding to the enzyme. By interfering with protein methylation, it modulates various cellular processes, including gene expression, protein stability, and cell signaling. Mechanism of action at the molecular level may be for studying the role of protein methylation in cellular physiology and processes.
Eosin Y Disodium Trihydrate (CAS 17372-87-1) References
- Small molecule regulators of protein arginine methyltransferases. | Cheng, D., et al. 2004. J Biol Chem. 279: 23892-9. PMID: 15056663
- Endothelial transcriptome in response to pharmacological methyltransferase inhibition. | Okabe, J., et al. 2014. ChemMedChem. 9: 1755-62. PMID: 24850797
- BTG1 potentiates apoptosis and suppresses proliferation in renal cell carcinoma by interacting with PRMT1. | Liu, C., et al. 2015. Oncol Lett. 10: 619-624. PMID: 26622543
- JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. | Kim, MS., et al. 2018. Sci Rep. 8: 6611. PMID: 29700375
- Stability of tuberous sclerosis complex 2 is controlled by methylation at R1457 and R1459. | Gen, S., et al. 2020. Sci Rep. 10: 21160. PMID: 33273660
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Eosin Y Disodium Trihydrate, 50 mg | sc-202776 | 50 mg | $119.00 | |||
Eosin Y Disodium Trihydrate, 500 mg | sc-202776A | 500 mg | $156.00 | |||
Eosin Y Disodium Trihydrate, 5 g | sc-202776B | 5 g | $198.00 | |||
Eosin Y Disodium Trihydrate, 50 g | sc-202776C | 50 g | $396.00 | |||
Eosin Y Disodium Trihydrate, 100 g | sc-202776D | 100 g | $676.00 |