Molecular structure of ent-8-iso Prostaglandin F2α-d9
ent-8-iso Prostaglandin F2α-d9
Alternate Names:
ent-8-epi PGF2α-d9
Application:
ent-8-iso Prostaglandin F2α-d9 is a labeled prostaglandin F2α analog which is formed via free radical peroxidation of AA
Molecular Weight:
363.5
Molecular Formula:
C20H25D9O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ent-8-iso Prostaglandin F2α-d9 is a labeled prostaglandin F2α (sc-201227) analog which is formed non-enzymatically via free radical peroxidation of Arachidonic Acid (sc-200770). This non-enzymatic production of biologically active prostaglandins is thought to limit the efficacy of Cox-2 inhibitors, and could potentially be used as a measure of oxidative stress. Ent-8-iso Prostaglandin F2α has been shown to be a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 31 and 54 nM, respectively. The deuterium atoms are located on carbons: 17, 18, 19, and 20.
ent-8-iso Prostaglandin F2α-d9 References
- Isomer-specific contractile effects of a series of synthetic f2-isoprostanes on retinal and cerebral microvasculature. | Hou, X., et al. 2004. Free Radic Biol Med. 36: 163-72. PMID: 14744628
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ent-8-iso Prostaglandin F2α-d9, 10 µg | sc-221588 | 10 µg | $185.00 | |||
ent-8-iso Prostaglandin F2α-d9, 25 µg | sc-221588A | 25 µg | $592.00 |