Date published: 2025-10-1

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Enrofloxacin-d5 (CAS 1173021-92-5)

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Alternate Names:
1-Cyclopropyl-7-[4-(ethyl-d5)-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; CFPQ-d5; Bay Vp 2674-d5; Baytril-d5
Application:
Enrofloxacin-d5 is a labeled fluorinated quinolone antibacterial
CAS Number:
1173021-92-5
Molecular Weight:
364.43
Molecular Formula:
C19H17D5FN3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Enrofloxacin-d5, an isotopically labeled variant of enrofloxacin, serves as a crucial tool in various scientific inquiries, particularly in pharmacokinetic studies and residue analysis in veterinary and environmental research. Its isotopic labeling with deuterium at specific positions allows for precise tracking of enrofloxacin and its metabolites in biological matrices and environmental samples. Researchers utilize enrofloxacin-d5 to investigate the pharmacokinetics of enrofloxacin and its metabolites in various animal species, elucidating absorption, distribution, metabolism, and excretion processes. Moreover, enrofloxacin-d5 facilitates residue analysis in food-producing animals by enabling accurate quantification of enrofloxacin residues and metabolites in animal tissues, milk, eggs, and other matrices. This contributes to ensuring food safety and assessing compliance with regulatory limits for veterinary drug residues in animal products. Furthermore, enrofloxacin-d5 finds application in environmental research, where it aids in tracking the fate and transport of enrofloxacin and its metabolites in aquatic and terrestrial environments, assessing their potential ecological impacts. Through advanced analytical techniques such as liquid chromatography-tandem mass spectrometry, researchers can detect and quantify enrofloxacin-d5 and its metabolites at trace levels, enhancing understanding of enrofloxacin′s behavior in biological and environmental systems.


Enrofloxacin-d5 (CAS 1173021-92-5) References

  1. Development of isotope dilution-liquid chromatography tandem mass spectrometry for the accurate determination of fluoroquinolones in animal meat products: optimization of chromatographic separation for eliminating matrix effects on isotope ratio measurements.  |  Lee, S., et al. 2013. J Chromatogr A. 1277: 35-41. PMID: 23332302
  2. Simultaneous Determination of Malachite Green, Chloramphenicols, Sulfonamides, and Fluoroquinolones Residues in Fish by Liquid Chromatography-Mass Spectrometry.  |  Chen, Y., et al. 2020. J Anal Methods Chem. 2020: 3725618. PMID: 32149000
  3. Amorphous poly-N-vinylcarbazole polymer as a novel matrix for the determination of low molecular weight compounds by MALDI-TOF MS.  |  Chen, XY., et al. 2022. RSC Adv. 12: 15215-15221. PMID: 35693227
  4. Confirming the presence of selected antibiotics and steroids in Norwegian biogas digestate.  |  Nesse, AS., et al. 2022. Environ Sci Pollut Res Int. 29: 86595-86605. PMID: 35796924
  5. Improved LC/MS/MS Quantification Using Dual Deuterated Isomers as the Surrogates: A Case Analysis of Enrofloxacin Residue in Aquatic Products.  |  Tang, Y., et al. 2023. Foods. 12: PMID: 36613439
  6. Screening of antibiotic residues in raw bovine milk in Lombardy, Italy: Microbial growth inhibition assay and LC-HRMS technique integration for an accurate monitoring.  |  Butovskaya, E., et al. 2023. Heliyon. 9: e15395. PMID: 37123980
  7. A Suitable HPLC-MS/MS Methodology for the Detection of Oxytetracycline, Enrofloxacin, and Sulfachloropyridazine Residues in Lettuce Plants.  |  Yévenes, K., et al. 2024. Foods. 13: PMID: 38201182
  8. Fate of fluoroquinolones in field soil environment after incorporation of poultry litter from a farm with enrofloxacin administration via drinking water.  |  Fučík, J., et al. 2024. Environ Sci Pollut Res Int. 31: 20017-20032. PMID: 38367114
  9. A modified QuEChERS-based UPLC-MS/MS method for rapid determination of multiple antibiotics and sedative residues in freshwater fish.  |  Yang, Y., et al. 2024. Food Chem X. 22: 101268. PMID: 38495454
  10. Development of a simple UPLC-MS/MS Method coupled with a modified QuEChERS for analyzing multiple antibiotics in vegetables and applied to pollution assessment  |  Yang, Y., Liu, L., Li, X., & Bao, R. 2024. Journal of Food Composition and Analysis. 129: 106135.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Enrofloxacin-d5, 1 mg

sc-218308
1 mg
$305.00