Enoxacin (CAS 74011-58-8)
See product citations (2)
QUICK LINKS
Enoxacin is a compound that is of interest in biochemistry and microbiology research, primarily for its interaction with bacterial enzymes. Its use in research focuses on studying the inhibition of bacterial DNA gyrase and topoisomerase IV, which are critical for DNA replication and cell division. Investigations involving Enoxacin often aim to understand the molecular basis of enzyme inhibition and the resistance mechanisms bacteria may develop. The compound serves as a tool to explore the efficacy and specificity of enzyme inhibitors, providing insights into the structural requirements for binding and activity. Additionally, Enoxacin is used in the study of bacterial biofilms, as it can influence their formation and stability, which is key to understanding bacterial survival strategies. Its role in the modulation of bacterial gene expression may also be examined, as compounds like Enoxacin can affect the quorum sensing pathways that bacteria use to communicate and coordinate their behavior.
Enoxacin (CAS 74011-58-8) References
- Bis-enoxacin inhibits bone resorption and orthodontic tooth movement. | Toro, EJ., et al. 2013. J Dent Res. 92: 925-31. PMID: 23958763
- Bis-enoxacin blocks rat alveolar bone resorption from experimental periodontitis. | Rivera, MF., et al. 2014. PLoS One. 9: e92119. PMID: 24638087
- Review of tissue penetration and clinical efficacy of enoxacin in skin and skin structure infections and in osteomyelitis. | Pankey, GA. 1989. Clin Pharmacokinet. 16 Suppl 1: 46-51. PMID: 2653695
- Clinical overview of enoxacin. | Zinner, SH. 1989. Clin Pharmacokinet. 16 Suppl 1: 59-64. PMID: 2653698
- [Enoxacin--comparative pharmacokinetics and tissue penetration]. | Sörgel, F., et al. 1989. Infection. 17 Suppl 1: S14-8. PMID: 2680989
- Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. | Pinto, S., et al. 2018. Redox Biol. 18: 84-92. PMID: 29986212
- Enoxacin and bis-enoxacin stimulate 4T1 murine breast cancer cells to release extracellular vesicles that inhibit osteoclastogenesis. | Vracar, TC., et al. 2018. Sci Rep. 8: 16182. PMID: 30385810
- Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. | Henwood, JM. and Monk, JP. 1988. Drugs. 36: 32-66. PMID: 3063494
- Enoxacin Up-Regulates MicroRNA Biogenesis and Down-Regulates Cytotoxic CD8 T-Cell Function in Autoimmune Cholangitis. | Itoh, A., et al. 2021. Hepatology. 74: 835-846. PMID: 33462854
- Enoxacin Exerts Anti-Tumor Effects Against Prostate Cancer Through Inducing Apoptosis. | Xu, H., et al. 2021. Technol Cancer Res Treat. 20: 1533033821995284. PMID: 33641532
- Targeting miRNA dysregulation with small molecules: the case of enoxacin. | Felicetti, T. and Manfroni, G. 2021. Future Med Chem. 13: 1245-1248. PMID: 34060341
- Enoxacin Shows Broad-Spectrum Antiviral Activity against Diverse Viruses by Enhancing Antiviral RNA Interference in Insects. | Lyu, B., et al. 2022. J Virol. 96: e0177821. PMID: 34908449
- Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections. | Patel, SS. and Spencer, CM. 1996. Drugs. 51: 137-60. PMID: 8741236
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Enoxacin, 500 mg | sc-205670 | 500 mg | $40.00 | |||
Enoxacin, 1 g | sc-205670A | 1 g | $49.00 |