Endophilin B1 Antibody (30A882): sc-52924

Endophilin B1 Antibody (30A882) is a mouse monoclonal IgG1 antibody that detects Endophilin B1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Endophilin B1 is a crucial member of the endophilin family, which plays a significant role in presynaptic vesicle trafficking at nerve terminals by interacting with proteins like Amphi-physin, Synaptojanin, and Dynamin. Endophilin B1 is essential for maintaining mitochondrial morphology and regulating the dynamics of the outer mitochondrial membrane, which is vital for cellular energy production and apoptosis. The N-terminal domain of Endophilin B1 exhibits high similarity to the lipid-binding and -modifying domain of class A endophilins, highlighting its potential role in lipid metabolism and membrane dynamics. Notably, the Endophilin B1 gene encodes at least three splice variants: Endophilin B1a, which is widely distributed across various tissues, and Endophilin B1b and B1c, which are primarily expressed in the brain, indicating a specialized function in neuronal health and signaling. With its diverse applications and critical biological functions, anti-Endophilin B1 antibody (30A882) is an invaluable tool for researchers studying synaptic function and mitochondrial dynamics.

The preferred Endophilin B1 antibody is Endophilin B1 Antibody (G-6): sc-374146.