Endophilin B1 Antibody (30A882): sc-52924
- Endophilin B1 Antibody (30A882) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against full length Endophilin B1 of human origin
- recommended for detection of Endophilin B1 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Endophilin B1 Antibody (30A882). This work is in progress.
QUICK LINKS
SEE ALSO...
Endophilin B1 Antibody (30A882) is a mouse monoclonal IgG1 antibody that detects Endophilin B1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Endophilin B1 is a crucial member of the endophilin family, which plays a significant role in presynaptic vesicle trafficking at nerve terminals by interacting with proteins like Amphi-physin, Synaptojanin, and Dynamin. Endophilin B1 is essential for maintaining mitochondrial morphology and regulating the dynamics of the outer mitochondrial membrane, which is vital for cellular energy production and apoptosis. The N-terminal domain of Endophilin B1 exhibits high similarity to the lipid-binding and -modifying domain of class A endophilins, highlighting its potential role in lipid metabolism and membrane dynamics. Notably, the Endophilin B1 gene encodes at least three splice variants: Endophilin B1a, which is widely distributed across various tissues, and Endophilin B1b and B1c, which are primarily expressed in the brain, indicating a specialized function in neuronal health and signaling. With its diverse applications and critical biological functions, anti-Endophilin B1 antibody (30A882) is an invaluable tool for researchers studying synaptic function and mitochondrial dynamics.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Endophilin B1 Antibody (30A882) References:
- Endophilin B1 as a novel regulator of nerve growth factor/ TrkA trafficking and neurite outgrowth. | Wan, J., et al. 2008. J Neurosci. 28: 9002-12. PMID: 18768694
- Endophilin B1: Guarding the gate to destruction. | Cheung, ZH. and Ip, NY. 2009. Commun Integr Biol. 2: 130-2. PMID: 19704909
- Bax activates endophilin B1 oligomerization and lipid membrane vesiculation. | Rostovtseva, TK., et al. 2009. J Biol Chem. 284: 34390-9. PMID: 19805544
- Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. | Wang, DB., et al. 2015. Brain. 138: 2005-19. PMID: 25981964
- Spatiotemporal Expression Patterns and Antibody Reactivity of Taeniidae Endophilin B1. | Ahn, CS., et al. 2016. J Clin Microbiol. 54: 2553-62. PMID: 27487955
- Association of Endophilin B1 with Cytoplasmic Vesicles. | Li, J., et al. 2016. Biophys J. 111: 565-576. PMID: 27508440
- Neuronal susceptibility to beta-amyloid toxicity and ischemic injury involves histone deacetylase-2 regulation of endophilin-B1. | Wang, DB., et al. 2019. Brain Pathol. 29: 164-175. PMID: 30028551
- Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis. | Touyama, K., et al. 2019. J Cell Biochem. 120: 18793-18804. PMID: 31243813
- Amphipathic Motifs Regulate N-BAR Protein Endophilin B1 Auto-inhibition and Drive Membrane Remodeling. | Bhatt, VS., et al. 2021. Structure. 29: 61-69.e3. PMID: 33086035
- Evaluation of recombinant glutathione transferase 26 kDa, thioredoxin-1, and endophilin B1 of Taenia solium in the diagnosis of human neurocysticercosis. | Jiménez, L., et al. 2022. Acta Trop. 227: 106294. PMID: 34963579
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Endophilin B1 Antibody (30A882) | sc-52924 | 100 µg/ml | $322.00 |