Date published: 2025-12-6

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Enalapril Maleate (CAS 76095-16-4)

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Application:
Enalapril Maleate is an angiotensin-converting enzyme inhibitor
CAS Number:
76095-16-4
Purity:
≥98%
Molecular Weight:
492.52
Molecular Formula:
C20H28N2O5•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Enalapril Maleate is an effective and potent nonsulfhydryl ACE(angiotenson-converting enzyme) inhibitor. The compound has been used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma. ACE inhibitors disturb the enin-angiotensin- aldosterone system. Additional ACE inhibitors include: Enalapril (sc-205664), Enalaprilat dihydrate (sc-205668), Enalaprilat (sc-205669), and Enalapril-d5 Maleate Salt (sc-218304), among others.


Enalapril Maleate (CAS 76095-16-4) References

  1. Changes of endothelin in streptozotocin-induced diabetic rats: effects of an angiotensin converting enzyme inhibitor, enalapril maleate.  |  Itoh, Y., et al. 2002. J Endocrinol. 175: 233-9. PMID: 12379508
  2. Identification of new impurities of enalapril maleate on oxidation in the presence of magnesium monoperoxyphthalate.  |  Toporisic, R., et al. 2010. J Pharm Biomed Anal. 52: 294-9. PMID: 20122808
  3. Formulation and evaluation of mucoadhesive buccal films of enalapril maleate.  |  Semalty, A., et al. 2010. Indian J Pharm Sci. 72: 571-5. PMID: 21694987
  4. Relevance of air-to-liquid mass ratio effect on final granule properties of an Enalapril maleate formulation.  |  Hartung, A., et al. 2012. Drug Dev Ind Pharm. 38: 12-8. PMID: 21721850
  5. Influence of different types of commercially available microcrystalline cellulose on degradation of perindopril erbumine and enalapril maleate in binary mixtures.  |  Vehovec, T., et al. 2012. Acta Pharm. 62: 515-28. PMID: 23333887
  6. Angiotensin-converting enzyme inhibitor (enalapril maleate) accelerates recovery of mouse skin from UVB-induced wrinkles.  |  Matsuura-Hachiya, Y., et al. 2013. Biochem Biophys Res Commun. 442: 38-43. PMID: 24216112
  7. Enhanced intestinal permeability and oral bioavailability of enalapril maleate upon complexation with the cationic polymethacrylate Eudragit E100.  |  Ramírez-Rigo, MV., et al. 2014. Eur J Pharm Sci. 55: 1-11. PMID: 24456933
  8. Proposal of a new degradation mechanism of enalapril maleate and improvement of enalapril maleate stability in tablet formulation with different stabilizers.  |  Chen, J., et al. 2014. Pharmazie. 69: 277-80. PMID: 24791591
  9. Improvement of enalapril maleate chemical stability by high shear melting granulation.  |  de Oliveira, APM., et al. 2015. Pharm Dev Technol. 20: 1002-1008. PMID: 25231642
  10. Effect of enalapril maleate on ghrelin levels in metabolic syndrome in rats.  |  Aygen, B., et al. 2015. Peptides. 67: 39-44. PMID: 25784288
  11. Enalapril: a new angiotensin converting enzyme inhibitor.  |  Cleary, JD. and Taylor, JW. 1986. Drug Intell Clin Pharm. 20: 177-86. PMID: 3007062
  12. The physiological disposition and metabolism of enalapril maleate in laboratory animals.  |  Tocco, DJ., et al. 1982. Drug Metab Dispos. 10: 15-9. PMID: 6124377
  13. Pharmacological properties of the converting enzyme inhibitor, enalapril maleate (MK-421).  |  Sweet, CS. 1983. Fed Proc. 42: 167-70. PMID: 6295819

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Enalapril Maleate, 1 g

sc-205666
1 g
$115.00

Enalapril Maleate, 5 g

sc-205666A
5 g
$399.00