Date published: 2026-10-17
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EMMPRIN/CD147 Antibody (1.BB.218) - Western Blotting - Image 377090
EMMPRIN 抗体 (1. BB. 218): sc-71038. HeLa (A), WI-38 (B) 和 A2058 (C) 全细胞裂解液中 EMMPRIN 表达的 Western 印迹分析.
EMMPRIN 抗体 (1. BB. 218): sc-71038. HeLa (A), WI-38 (B) 和 A2058 (C) 全细胞裂解液中 EMMPRIN 表达的 Western 印迹分析.

EMMPRIN/CD147 抗体 (1.BB.218): sc-71038

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说明书
  • EMMPRIN/CD147抗体(1.BB.218)是小鼠单克隆IgG1 κ, 在29篇文献中引用，规格为200 µg/ml
  • 针对human T细胞白血病细胞系，Peer
  • 推荐用于 human 来源的EMMPRIN WB, IP, IF, IHC(P) 和 FCM检测
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是EMMPRIN/CD147 Antibody (1.BB.218) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与EMMPRIN/CD147 Antibody (1.BB.218) 打包提供（请参阅下面的订购信息）。
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EMMPRIN/CD147抗体（1.BB.218）是一种IgG1κ小鼠单克隆EMMPRIN抗体，可通过WB、IP、IF、IHC（P）和FCM检测人源EMMPRIN。EMMPRIN/CD147抗体（1.BB.218）可作为非共轭抗EMMPRIN抗体形式提供。细胞外基质金属蛋白酶诱导因子（EMMPRIN），也称为basigin或CD147，参与调节表皮-真皮界面处的基质重塑。EMMPRIN刺激成纤维细胞产生间质胶原酶、明胶酶A、基质分解素-1和各种金属蛋白酶（MMP）。这些酶通常在组织降解和伤口愈合过程中增加，是癌症侵袭和转移的重要因素。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

EMMPRIN/CD147 抗体 (1.BB.218) 参考文献:

  1. EMMPRIN介导心脏肌细胞中β-肾上腺素能受体刺激的基质金属蛋白酶活性。  |  Siwik, DA., et al. 2008. J Mol Cell Cardiol. 44: 210-7. PMID: 17869266
  2. EMMPRIN（CD147）是血小板GPVI的新型受体，通过GPVI-EMMPRIN相互作用介导血小板滚动。  |  Seizer, P., et al. 2009. Thromb Haemost. 101: 682-6. PMID: 19350111
  3. EMMPRIN通过缺氧诱导因子-2α介导的可溶性VEGF同种型及其受体VEGFR-2的调节促进血管生成。  |  Bougatef, F., et al. 2009. Blood. 114: 5547-56. PMID: 19837976
  4. miR-485-5p参与肝癌进展，靶向EMMPRIN。  |  Sun, X., et al. 2015. Biomed Pharmacother. 72: 58-65. PMID: 26054676
  5. EMMPRIN通过SDF-1和VEGF的旁分泌信号，招募骨髓来源的细胞，从而调节肿瘤的生长和转移。  |  Chen, Y., et al. 2015. Oncotarget. 6: 32575-85. PMID: 26416452
  6. EMMPRIN 通过下调miR-106a/b，通过与成纤维细胞的相互作用，通过STAT3和HIF-1α改变乳腺癌干细胞样细胞的特性。  |  Liu, Y., et al. 2016. Sci Rep. 6: 28329. PMID: 27325313
  7. 牙周炎中Wnt/β-catenin信号通路与EMMPRIN/MMP-2、9途径之间的相互作用。  |  Liu, X., et al. 2018. J Periodontal Res. 53: 842-852. PMID: 29900539
  8. CD73与emmprin复合，调节共培养肉瘤细胞和成纤维细胞中MMP-2的产生。  |  Aoki, M., et al. 2019. BMC Cancer. 19: 912. PMID: 31510956
  9. EMMPRIN/CD147在调节银屑病关节炎患者血管生成中的作用。  |  Rahat, MA., et al. 2020. Arthritis Res Ther. 22: 240. PMID: 33054815
  10. EMMPRIN促进球状组织和转移的形成：CT26结肠癌细胞单层和球状细胞之间的比较。  |  Feigelman, G., et al. 2024. Front Immunol. 15: 1374088. PMID: 38725999

订购信息

产品名称产品编号规格价格数量收藏夹

EMMPRIN/CD147 抗体 (1.BB.218)

sc-71038
200 µg/ml
$322.00

EMMPRIN/CD147 (1.BB.218): m-IgG Fc BP-HRP 套装

sc-528653
200 µg Ab; 10 µg BP
$361.00

EMMPRIN/CD147 (1.BB.218): m-IgGκ BP-HRP 套装

sc-521093
200 µg Ab, 40 µg BP
$361.00

EMMPRIN/CD147 (1.BB.218): m-IgG1 BP-HRP 套装

sc-543055
200 µg Ab; 20 µg BP
$361.00

Why isn't EMMPRIN Antibody (1.BB.218) available in FITC, PE, APC conjugates for flow cytometry? Is it because the antibody recognizes trans-membrane or cytoplasmic domain of the protein?

Asked by: Vishal Menon
Thank you for your question. We don't offer all our antibodies conjugated to all the fluorochromes, this is not feasible. However, we can usually offer them as as a special order. Please contact our European Technical Service team and they would be happy to help you see if we can provide this antibody conjugated to any fluorochrome you are interested in! You can reach them by phone at Toll Free: +49 6221 4503 0, by email at: europe@scbt.com or by live chat directly on our website, www.scbt.com
Answered by: Tech Service
Date published: 2017-06-12

What is the recommended starting dilution for Western blot for sc-71038: EMMPRIN (1.BB.218) monoclonal antibody?

Asked by: Dr Ninau Qelp
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by paula827 from 条带很清晰条带很清晰，抗体的用量也不大。非常喜欢santa可以4度保存的液体抗体，使用起来非常方便。购买的体验也不错！
Date published: 2017-12-19
Rated 4 out of 5 by GRANJA from Good for Western blotIt work well, with strong signal for western blot
Date published: 2017-10-31
Rated 5 out of 5 by Cweed from Provides appropriate detectionThis antibody will detect the correct protein in staining and blotting applications. The staining is clear with strong signal. This antibody is has been cited in several published papers.
Date published: 2017-02-08
Rated 4 out of 5 by FL from Positive signal observed in WB in SKPositive signal observed in WB in SK-MEL-28 and HeLa whole cell lysates. -SCBT QC
Date published: 2015-06-19
Rated 4 out of 5 by MS from Published IHC(P) data for use in human bladderPublished IHC(P) data for use in human bladder cancers and non-cancerous tissue. -SCBT Publication Review
Date published: 2015-05-27
Rated 4 out of 5 by TS from Publishable data for IHC and WB in humanPublishable data for IHC and WB in human breast cancer cell lines. -SCBT Publication Review
Date published: 2015-04-21
Rated 4 out of 5 by SM from Published IHC data for use in human lymph nodePublished IHC data for use in human lymph node. -SCBT Publication Review
Date published: 2015-03-28
Rated 4 out of 5 by JL from Published IHC(Pfa) data for use in humanPublished IHC(Pfa) data for use in human IHCCA tissues. -SCBT Publication Review
Date published: 2015-03-24
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EMMPRIN/CD147 抗体 (1.BB.218) is rated 4.2 out of 5 by 10.
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