EMD 66684 CAS: 187683-79-0
MF: C28H30N8O2•HCl
MW: 547.05
A potent non-peptidic antagonist of the AT1 receptor.

EMD 66684 (CAS 187683-79-0)

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Application: EMD 66684 is a potent non-peptidic antagonist of the AT1 receptor
CAS Number: 187683-79-0
Molecular Weight: 547.05
Molecular Formula: C28H30N8O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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EMD 66684 is a potent, selective nonpeptide AT1 receptor antagonist. This compound prevents the binding of angiotensin II to the receptor, which blocks the signal cascade that induces vasoconstricition.


References

1. Mederski, W.W., et al. 1994. J. Med. Chem. 37: 1632-1645. PMID: 8201597

Physical State :
Solid
Solubility :
Soluble to 50 mM in DMSO and to 50 mM in Ethanol
Storage :
Desiccate at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
56972165
SMILES :
CCCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)N(C=C2)CC(=O)N(C)C.Cl

Download SDS (MSDS)

Certificate of Analysis

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