Molecular structure of Emamectin B1a, CAS Number: 121124-29-6
Emamectin B1a (CAS 121124-29-6)
Application:
Emamectin B1a is a semi-synthetic analogue of avermecting B1a with enhanced insecticidal potency
CAS Number:
121124-29-6
Molecular Weight:
886.12
Molecular Formula:
C49H75NO13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Emamectin B1a is a semi-synthetic 4"-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4"-hydroxy moiety and reductive amination. The introduction of the methylamino group greatly enhances the insecticidal potency of the avermectin class. Emamectin B1a, as a benzoate salt, is the major component (>90%) of the commercial insecticide/acaricide, emamectin. Members of the avermectin/milbemycin class exert their insecticidal/anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells.
Emamectin B1a (CAS 121124-29-6) References
- Simultaneous determination of residues of emamectin and its metabolites, and milbemectin, ivermectin, and abamectin in crops by liquid chromatography with fluorescence detection. | Yoshii, K., et al. 2001. J AOAC Int. 84: 910-7. PMID: 11417654
- Determination of emamectin residues in the tissues of Atlantic salmon (Salmo salar L.) using HPLC with fluorescence detection. | Kim-Kang, H., et al. 2001. J Agric Food Chem. 49: 5294-302. PMID: 11714319
- Liquid chromatography/fluorescence method for emamectin B1a and desmethylamino-emamectin B1a residues in lobster tissue. | Tauber, R., et al. 2006. J AOAC Int. 89: 1672-6. PMID: 17225616
- Environmental fate of emamectin benzoate after tree micro injection of horse chestnut trees. | Burkhard, R., et al. 2015. Environ Toxicol Chem. 34: 297-302. PMID: 25363584
- Ameliorative effect of vitamin C against hepatotoxicity induced by emamectin benzoate in rats. | Khaldoun Oularbi, H., et al. 2017. Hum Exp Toxicol. 36: 709-717. PMID: 27461011
- Modification of the existing maximum residue levels for emamectin in kiwi and peaches. | ,., et al. 2019. EFSA J. 17: e05710. PMID: 32626333
- Modification of the existing maximum residue levels for emamectin in various crops. | ,., et al. 2021. EFSA J. 19: e06824. PMID: 34484450
- Comparative Bioactivity of Emamectin Benzoate Formulations against the Pine Wood Nematode, Bursaphelenchus xylophilus. | Lee, JW., et al. 2023. Plant Pathol J. 39: 75-87. PMID: 36760051
- Biosafety, histological alterations and residue depletion of feed administered anti-parasitic drug emamectin benzoate in golden mahseer, Tor putitora (Hamilton, 1822) as a model candidate fish for sport fishery and conservation in temperate waters. | Mallik, SK., et al. 2023. Front Pharmacol. 14: 1106124. PMID: 36843939
- Acute toxicity of emamectin benzoate (SLICE™) in fish feed to American lobster, Homarus americanus | Burridge, L. E., Hamilton, N., Waddy, S. L., Haya, K., Mercer, S. M., Greenhalgh, R.,.. & Endris, R. G. 2004. Aquaculture Research. 35(8): 713-722.
- Simultaneous Determination of Emamectin, its Metabolites, Milbemectin, Ivermectin and Abamectin in Tomato, Japanese Radish and Tea by LC/MS | Yoshii, K., Ishimitsu, S., Tonogai, Y., Arakawa, K., Murata, H., & Mikami, H. 2004. Journal of health science. 50(1): 17-24.
- Depletion of emamectin residues following oral administration to rainbow trout, Oncorhynchus mykiss | Roy, W. J., Gillan, N., Crouch, L., Parker, R., Rodger, H., & Endris, R. 2006. Aquaculture. 259(1-4): 6-16.
- Plasma and kidney distribution of emamectin benzoate in rats by ultra-performance liquid chromatography–tandem mass spectrometry, and protective effect of vitamin C | Khaldoun-Oularbi, H., Richeval, C., & Allorge, D. 2015. Toxicologie Analytique et Clinique. 27(2): S64.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Emamectin B1a, 1 mg | sc-391524 | 1 mg | $515.00 | |||
Emamectin B1a, 5 mg | sc-391524A | 5 mg | $1350.00 |