ELOVL5 (m): 293T Lysate: sc-120012

The ELOVL5 (m): 293T Lysate is derived from the HEK293T cell line, a human embryonic kidney cell line renowned for its high transfection efficiency, making it a robust tool in molecular and cellular biology research. This lysate contains ELOVL5, a member of the ELOVL (Elongation of Very Long Chain Fatty Acids) family, specifically involved in the elongation of polyunsaturated fatty acids (PUFAs). ELOVL5 plays a critical role in lipid metabolism by catalyzing the addition of two-carbon units to long-chain fatty acids, extending their length. This enzymatic activity is crucial for the biosynthesis of essential PUFAs, which are important components of cell membranes and precursors for bioactive lipid mediators. In research, the ELOVL5 (m): 293T Lysate is used to study the enzymatic mechanisms and regulatory pathways of fatty acid elongation. Researchers utilize this lysate in in vitro assays to examine the substrate specificity of ELOVL5, identify potential regulatory proteins and post-translational modifications, and screen for modulators of ELOVL5 activity. This lysate is instrumental in elucidating the role of ELOVL5 in lipid homeostasis and its impact on cellular functions such as membrane fluidity, signaling, and energy metabolism. By leveraging this lysate, scientists gain valuable insights into the complexities of lipid biosynthesis and its broader implications in cellular physiology and metabolism.