Date published: 2025-10-14

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Elmycin B (CAS 128233-09-0)

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Alternate Names:
(1aR,3S,5bR,11S,11aR,11bR)-10,11,11a-Trihydroxy-3-methyl-3,4,5b,11,11a,11b-hexahydrotetrapheno[5,6-b]oxirene-5,6(1aH,2H)-dione
Application:
Elmycin B is an angucyclinone antibiotic with moderate cytotoxic activity
CAS Number:
128233-09-0
Molecular Weight:
342.34
Molecular Formula:
C19H18O6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Belonging to the elmycin family, Elmycin B stands as a noteworthy compound class encompassing a diverse range of antibiotic and antifungal agents. Demonstrating remarkable potency, Elmycin B acts as a robust inhibitor against both Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis, and Gram-negative bacteria, such as Escherichia coli and Pseudomonas aeruginosa. The mechanism of action for Elmycin B involves the inhibition of bacterial growth through the blockade of protein synthesis, encompassing enzymes and other proteins vital to cell division and metabolism. Notably, Elmycin B exhibits an additional impact on bacterial cell walls, rendering them more permeable and consequently heightening their susceptibility to antibiotics. Moreover, this compound has demonstrated the ability to inhibit the activity of specific enzymes involved in DNA and RNA synthesis, further expanding its spectrum of antibacterial effects.


Elmycin B (CAS 128233-09-0) References

  1. Angucycline group antibiotics.  |  Rohr, J. and Thiericke, R. 1992. Nat Prod Rep. 9: 103-37. PMID: 1620493
  2. Angucyclinones from an Indonesian Streptomyces sp.  |  Fotso, S., et al. 2008. J Nat Prod. 71: 61-5. PMID: 18081255
  3. Biosynthesis of PD 116740: origins of the carbon, hydrogen, and oxygen atoms and derivation from a 6-deoxybenz[a]anthraquinone  |  Steven J. Gould, Xingchun Cheng, and Chris Melville. 1994,. J. Am. Chem. Soc. 116, 5,: 1800–1804.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Elmycin B, 1 mg

sc-202599
1 mg
$294.00

Elmycin B, 5 mg

sc-202599A
5 mg
$930.00