Molecular structure of EITC, CAS Number: 72814-84-7
EITC (CAS 72814-84-7)
Alternate Names:
Erythrosin isothiocyanate
Application:
EITC is a thiocyanate fluorescein derivative molecular probe
CAS Number:
72814-84-7
Molecular Weight:
892.97
Molecular Formula:
C21H7I4NO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
EITC is a thiocyanate fluorescein derivative molecular probe. EITC is a member of lysine-reactive dyes. This fluorescent dye specifically reacts with lysine residues found in proteins. EITC finds utility in quantifying epidermal growth factor levels in biological samples, and its fluorescence can be observed using a microscope or spectrophotometer. Upon binding to proteins, EITC induces a reduction in fluorescence intensity, enabling detection through changes in the emitted light′s wavelength at 590 nm. Additionally, EITC acts as an inhibitor of tyrosine kinase activity, preventing the influx of calcium ions into cells.
EITC (CAS 72814-84-7) References
- Lysophosphatidylcholine modulates catalytically important motions of the Ca-ATPase phosphorylation domain. | Hunter, GW., et al. 1999. Biochemistry. 38: 4604-12. PMID: 10194382
- Effects of melittin on molecular dynamics and Ca-ATPase activity in sarcoplasmic reticulum membranes: time-resolved optical anisotropy. | Voss, J., et al. 1991. Biochemistry. 30: 7498-506. PMID: 1649630
- Protein rotation, enzyme activity and photooxidation of SH groups in sarcoplasmic reticulum Ca2+-ATPase. | Restall, CJ., et al. 1981. Biochim Biophys Acta. 670: 433-40. PMID: 6457648
- Protein and lipid rotational dynamics in cardiac and skeletal sarcoplasmic reticulum detected by EPR and phosphorescence anisotropy. | Birmachu, W., et al. 1993. Biochemistry. 32: 9445-53. PMID: 8396431
- Differential effects of general anesthetics on the quaternary structure of the Ca-ATPases of cardiac and skeletal sarcoplasmic reticulum. | Kutchai, H., et al. 1998. Biochemistry. 37: 2410-21. PMID: 9485389
- Erythrosin isothiocyanate selectively labels lysine464 within an ATP-protectable binding site on the Ca-ATPase in skeletal sarcoplasmic reticulum membranes. | Huang, S., et al. 1998. Biochemistry. 37: 6949-57. PMID: 9578581
- Enhanced rotational dynamics of the phosphorylation domain of the Ca-ATPase upon calcium activation. | Huang, S. and Squier, TC. 1998. Biochemistry. 37: 18064-73. PMID: 9922175
- Phosphatidylethanolamine modulates Ca-ATPase function and dynamics. | Hunter, GW., et al. 1999. Biochemistry. 38: 1356-64. PMID: 9930998
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EITC, 50 mg | sc-263115 | 50 mg | $556.00 |