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Eicosa-11Z,14Z-dienoic Acid (CAS 2091-39-6)

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Alternate Names:
cis-11,14-Eicosadienoic acid
Application:
Eicosa-11Z,14Z-dienoic Acid is a polyunsaturated lipid analog of arachidonic acid that inhibits calcineurin
CAS Number:
2091-39-6
Molecular Weight:
308.50
Molecular Formula:
C20H36O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Eicosa-11Z,14Z-dienoic acid is an unsaturated fatty acid that is often a subject of interest in nutritional and metabolic studies. This compound contains two cis double bonds located at the 11th and 14th carbon atoms, which is indicative of the configuration and position of unsaturation within the carbon chain. Research on eicosa-11Z,14Z-dienoic acid typically involves its role in cellular signaling pathways and its metabolism within the body. It is relevant in the study of lipid-derived mediators, which are critical in cellular communication and the regulation of physiological processes. Eicosa-11Z,14Z-dienoic acid is also important in the investigation of lipid biosynthesis pathways, as it may serve as a precursor or intermediate in the production of other biologically active lipids. In addition, due to its structural characteristics, this fatty acid is utilized in research to understand the effects of fatty acid composition on the fluidity and function of cellular membranes. The compound is also of interest in the field of food science where researchers explore the impact of various fatty acids on the nutritional properties of dietary fats and oils.


Eicosa-11Z,14Z-dienoic Acid (CAS 2091-39-6) References

  1. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.  |  Briscoe, CP., et al. 2003. J Biol Chem. 278: 11303-11. PMID: 12496284
  2. Inhibition of calcineurin by polyunsaturated lipids.  |  Tokheim, AM. and Martin, BL. 2006. Bioorg Chem. 34: 66-76. PMID: 16464485
  3. The positive feedback role of arachidonic acid in the platelet-derived growth factor-induced signaling in lens epithelial cells.  |  Zhang, W., et al. 2006. Mol Vis. 12: 821-31. PMID: 16902399
  4. Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells.  |  Cui, XL. and Douglas, JG. 1997. Proc Natl Acad Sci U S A. 94: 3771-6. PMID: 9108053
  5. The presence of an endogenous superoxide anion-generating system in the cells.  |  Zhang, W. and M. F. Lou. 2003. Investigative Ophthalmology & Visual Science. 44.13: 316-316.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Eicosa-11Z,14Z-dienoic Acid, 100 mg

sc-200776
100 mg
$31.00

Eicosa-11Z,14Z-dienoic Acid, 1 g

sc-200776A
1 g
$162.00