EGR1 Antibody (H-7): sc-515889
- EGR1 Antibody (H-7) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 519-543 at the C-terminus of Egr-1 of human origin
- recommended for detection of Egr-1 p82 of human origin by WB, IP, IF, IHC(P) and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications (sc-515889 X, 200 µg/0.1 ml)
- m-IgGκ BP-HRP is the preferred secondary detection reagent for EGR1 Antibody (H-7) for WB and IHC(P) applications. This reagent is now offered in a bundle with EGR1 Antibody (H-7) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Egr-1 Antibody (H-7) is a mouse monoclonal IgG2b antibody that detects Egr-1 in human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Egr-1, a member of the early growth response (Egr) family of transcription factors, plays a crucial role in cellular processes such as mitogenesis and differentiation by binding to specific DNA sequences, notably the Egr-site (5′-CGCCCCCGC-3′), to activate the transcription of target genes. This function is vital for regulating cellular responses to external stimuli, as anti-Egr-1 antibody (H-7) detects a protein rapidly induced by various signals, highlighting Egr-1′s importance in immediate early gene expression. Egr-1′s activity is tightly regulated through multiple mechanisms, including transcriptional, translational, and post-translational modifications such as phosphorylation and glycosylation, which can influence stability and interaction with other proteins. Egr-1′s ability to modulate gene expression in response to environmental cues underscores significance in developmental processes and potential implications in various diseases, making Egr-1 (H-7) antibody an essential tool for researchers studying these critical biological pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EGR1 Antibody (H-7) | sc-515889 | 200 µg/ml | $316.00 | |||
EGR1 Antibody (H-7): m-IgGκ BP-HRP Bundle | sc-525269 | 200 µg Ab, 40 µg BP | $354.00 | |||
EGR1 Antibody (H-7) X | sc-515889 X | 200 µg/0.1 ml | $316.00 |