Molecular structure of EGF/FGF/PDGF receptor tyrosine kinase inhibitor, CAS Number: 1135256-66-4
EGF/FGF/PDGF receptor tyrosine kinase inhibitor Inhibitor (CAS 1135256-66-4)
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Alternate Names:
1-(2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butyl urea; PDGFR Tyrosine Kinase Inhibitor XIII
Application:
EGF/FGF/PDGF receptor tyrosine kinase inhibitor is a tyrosine kinase inhibitor that inhibits human FGFR-1, PDGFR-β, c-Scr, & EGFR
CAS Number:
1135256-66-4
Purity:
≥97%
Molecular Weight:
405.28
Molecular Formula:
C18H18Cl2N6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor is a cell-permeable and reversible protein tyrosine kinase inhibitor that inhibits human FGFR-1, PDGFR-β, c-Scr, and EGFR, meanwhile exhibiting minimal activity against InsR, PKC, or CDK4/Cyclin D1. Inhibition by EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor is shown to be noncompetitive in the case of c-Src, but ATP-competitive in the case of FGFR-1, PDGFR-β, and EGFR.
Inhibitor of:
c-Src, EGFR, Flg, and PDGFR-beta.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EGF/FGF/PDGF receptor tyrosine kinase inhibitor, 2 mg | sc-221579 | 2 mg | $290.00 |