EG00229 (CAS 1210945-69-9)
Alternate Names:
EG00229 EG 00229 EG-00229
CAS Number:
1210945-69-9
Molecular Weight:
611.60
Molecular Formula:
C19H20F3N7O7S3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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EG00229 (CAS 1210945-69-9) References
- Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway. | Nissen, JC., et al. 2013. J Neurochem. 127: 394-402. PMID: 24033337
- Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression. | Miyauchi, JT., et al. 2016. Oncotarget. 7: 9801-14. PMID: 26755653
- Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells. | Powell, J., et al. 2018. J Med Chem. 61: 4135-4154. PMID: 29648813
- Synchronous inhibition of mTOR and VEGF/NRP1 axis impedes tumor growth and metastasis in renal cancer. | Pal, K., et al. 2019. NPJ Precis Oncol. 3: 31. PMID: 31840081
- In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein. | Perez-Miller, S., et al. 2020. bioRxiv.. PMID: 32995772
- SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia. | Moutal, A., et al. 2021. Pain. 162: 243-252. PMID: 33009246
- Molecular basis of the new COVID-19 target neuropilin-1 in complex with SARS-CoV-2 S1 C-end rule peptide and small-molecule antagonists. | Klaewkla, M., et al. 2021. J Mol Liq. 335: 116537. PMID: 34031621
- Effect of EG00229 on Radiation Resistance of Lung Adenocarcinoma Cells. | Cong, L., et al. 2021. J Cancer. 12: 6105-6117. PMID: 34539883
- Novel Small-Molecule Inhibitors of the SARS-CoV-2 Spike Protein Binding to Neuropilin 1. | Kolarič, A., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 35215277
- Tuftsin ameliorates splenic inflammatory injury by promoting neuropilin-1 in severe acute pancreatitis. | Wen, E., et al. 2022. Biochem Pharmacol. 199: 115030. PMID: 35381211
Inhibitor of:
Endoglin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EG00229, 50 mg | sc-507329 | 50 mg | $1300.00 |