Molecular structure of Efaroxan hydrochloride, CAS Number: 89197-00-2
Efaroxan hydrochloride (CAS 89197-00-2)
Application:
Efaroxan hydrochloride is a potent α2-AR adrenoceptor antagonist
CAS Number:
89197-00-2
Purity:
≥99%
Molecular Weight:
252.74
Molecular Formula:
C13H16N2O•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Efaroxan hydrochloride promotes insulin secretion, at a site distinct from I1 or I2 (the putative I3 receptor) in vitro. Efaroxan hydrochloride is a potent, highly selective α2-AR adrenoceptor antagonist and imidazoline I1 receptor ligand (pKi values are 7.87, 7.42, 5.74, 7.28 and < 5 for α2A-AR , α2B-AR , α2C-AR , Ι1 and Ι2 receptors, respectively).
Efaroxan hydrochloride (CAS 89197-00-2) References
1. Chapleo, C.B., et al. 1984. J. Med. Chem. 27: 570-576.2. Olmos, G., et al. 1994. Eur. J. Pharmacol. 262: 41-48.
3. Eglen, R,.M., et al. 1998. Trends Pharmacol Sci. 19: 381-390.
4. Mayer, G. and Taberner, P.V. 2002. Eur. J. Pharmacol. 454: 95.
Inhibitor of:
alpha2A-AR, and alpha2B-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Efaroxan hydrochloride, 10 mg | sc-203573 | 10 mg | $125.00 | |||
Efaroxan hydrochloride, 50 mg | sc-203573A | 50 mg | $525.00 |