EEPD1 Antibody (B-5): sc-398019
- EEPD1 Antibody (B-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 501-569 mapping at the C-terminus of EEPD1 of human origin
- EEPD1 Antibody (B-5) is recommended for detection of EEPD1 of human origin by WB, IP, IF and ELISA
- Anti-EEPD1 Antibody (B-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EEPD1 Antibody (B-5) for WB applications. These reagents are now offered in bundles with EEPD1 Antibody (B-5) (see ordering information below).
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EEPD1 Antibody (B-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects EEPD1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-EEPD1 antibody (B-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. EEPD1, also known as endonuclease/exonuclease/phosphatase family domain containing 1 or HSPC107, is a 569 amino acid protein characterized by the presence of one helix-hairpin-helix (HhH) domain, which is crucial for DNA binding and repair. EEPD1′s function is particularly important in maintaining genomic stability, a vital process for preventing mutations that can lead to various diseases, including cancer. EEPD1 expression is significantly affected by environmental stressors; for instance, long-term heat stress exposure leads to a marked decrease in transcriptional levels, while EEPD1 is up-regulated during bovine adipogenic processes associated with intramuscular preadipocyte differentiation. Encoded by a gene located on human chromosome 7p14.2, EEPD1 plays a pivotal role in cellular responses to DNA damage, and chromosome 7 itself is known to harbor genes linked to several genetic disorders, including osteogenesis imperfecta and Pendred syndrome.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
EEPD1 Antibody (B-5) References:
- The DNA sequence of human chromosome 7. | Hillier, LW., et al. 2003. Nature. 424: 157-64. PMID: 12853948
- Lissencephaly 1 linking to multiple diseases: mental retardation, neurodegeneration, schizophrenia, male sterility, and more. | Reiner, O., et al. 2006. Neuromolecular Med. 8: 547-65. PMID: 17028375
- Structural aberrations of chromosome 7 revealed by a combination of molecular cytogenetic techniques in myeloid malignancies. | Brezinová, J., et al. 2007. Cancer Genet Cytogenet. 173: 10-6. PMID: 17284364
- Therapy-related leukemia and myelodysplasia: susceptibility and incidence. | Leone, G., et al. 2007. Haematologica. 92: 1389-98. PMID: 17768113
- Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response. | Trevisan, M., et al. 2009. J Cell Physiol. 221: 629-41. PMID: 19688782
- Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease. | Dubinsky, MC., et al. 2010. Inflamm Bowel Dis. 16: 1357-66. PMID: 20014019
- Differentially expressed genes during bovine intramuscular adipocyte differentiation profiled by serial analysis of gene expression. | Mizoguchi, Y., et al. 2010. Anim Genet. 41: 436-41. PMID: 20219066
- Responses of muscle mass, strength and gene transcripts to long-term heat stress in healthy human subjects. | Goto, K., et al. 2011. Eur J Appl Physiol. 111: 17-27. PMID: 20803152
- Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta. | Tsipouras, P., et al. 1983. J Clin Invest. 72: 1262-7. PMID: 6313757
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EEPD1 Antibody (B-5) | sc-398019 | 200 µg/ml | $322.00 | |||
EEPD1 Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-530663 | 200 µg Ab; 10 µg BP | $361.00 | |||
EEPD1 Antibody (B-5): m-IgGκ BP-HRP Bundle | sc-524183 | 200 µg Ab, 40 µg BP | $361.00 | |||
EEPD1 Antibody (B-5): m-IgG1 BP-HRP Bundle | sc-544189 | 200 µg Ab; 20 µg BP | $361.00 | |||
EEPD1 Antibody (B-5) AC | sc-398019 AC | 500 µg/ml, 25% agarose | $424.00 | |||
EEPD1 Antibody (B-5) HRP | sc-398019 HRP | 200 µg/ml | $322.00 | |||
EEPD1 Antibody (B-5) FITC | sc-398019 FITC | 200 µg/ml | $336.00 | |||
EEPD1 Antibody (B-5) PE | sc-398019 PE | 200 µg/ml | $349.00 | |||
EEPD1 Antibody (B-5) Alexa Fluor® 488 | sc-398019 AF488 | 200 µg/ml | $364.00 | |||
EEPD1 Antibody (B-5) Alexa Fluor® 546 | sc-398019 AF546 | 200 µg/ml | $364.00 | |||
EEPD1 Antibody (B-5) Alexa Fluor® 594 | sc-398019 AF594 | 200 µg/ml | $364.00 | |||
EEPD1 Antibody (B-5) Alexa Fluor® 647 | sc-398019 AF647 | 200 µg/ml | $364.00 | |||
EEPD1 Antibody (B-5) Alexa Fluor® 680 | sc-398019 AF680 | 200 µg/ml | $364.00 | |||
EEPD1 Antibody (B-5) Alexa Fluor® 790 | sc-398019 AF790 | 200 µg/ml | $364.00 |