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EDTA, Disodium Salt, Dihydrate (CAS 6381-92-6)

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Alternate Names:
Disodium ethylenediaminetetraacetatedihydrate;Edetatedisodium saltdihydrate
Application:
EDTA, Disodium Salt, Dihydrate is a chelating agent for metal ions; minimizes metal ion impurities in reaction buffers
CAS Number:
6381-92-6
Purity:
≥99%
Molecular Weight:
372.2
Molecular Formula:
C10H14N2Na2O82H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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EDTA, Disodium Salt, Dihydrate is an extensively used chelator of divalent cations such as Ca2+. EDTA (Ethylenediaminetetraacetic acid) is a chelating agent, a general chemical, and a sequestrant. In molecular biology applications, it is used to minimize metal ion contaminants. Also, it can facilitate enzymatic reactions that could be inhibited by heavy metal traces. On the other hand, it can inhibit enzymes, such as metalloproteases, that require divalent cations for activity.


EDTA, Disodium Salt, Dihydrate (CAS 6381-92-6) References

  1. Biodegradation of EDTA.  |  Nörtemann, B. 1999. Appl Microbiol Biotechnol. 51: 751-9. PMID: 10422222
  2. Use of bacteriophage endolysin EL188 and outer membrane permeabilizers against Pseudomonas aeruginosa.  |  Briers, Y., et al. 2011. J Appl Microbiol. 110: 778-85. PMID: 21241420
  3. Determination of residual fluoroquinolones in honey by liquid chromatography using metal chelate affinity chromatography.  |  Yatsukawa, Y., et al. 2011. J AOAC Int. 94: 1319-27. PMID: 21919363
  4. Evaluation of the double-disk synergy test for New Delhi metallo-β-lactamase-1 and other metallo-β-lactamase producing gram-negative bacteria by using metal-ethylenediaminetetraacetic acid complexes.  |  Fujisaki, M., et al. 2013. Microbiol Immunol. 57: 346-52. PMID: 23668606
  5. Improved nonreductive O-glycan release by hydrazinolysis with ethylenediaminetetraacetic acid addition.  |  Kozak, RP., et al. 2014. Anal Biochem. 453: 29-37. PMID: 24613257
  6. Evaluation of ethylenediaminetetraacetic acid, tetrasodium salt dihydrate (EDTA)-Tween 20 treatment versus protease digestion of formalin-fixed tissue sections for detection of bovine respiratory syncytial virus antigen in infected ovine lung.  |  Meehan, JT., et al. 1989. Vet Pathol. 26: 322-5. PMID: 2503919
  7. Synergetic activation of persulfate by heat and Fe(II)-complexes for hydrolyzed polyacrylamide degradation at high pH condition: Kinetics, mechanism, and application potential for filter cake removal during cementing in CO2 storage wells.  |  Huang, S., et al. 2020. Sci Total Environ. 713: 136561. PMID: 31954243
  8. Multi-Class Procedure for Analysis of 50 Antibacterial Compounds in Eggshells Using Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry.  |  Gbylik-Sikorska, M., et al. 2021. Molecules. 26: PMID: 33806573
  9. Photopolymerization with EDTA and Riboflavin for Proteins Analysis in Polyacrylamide Gel Electrophoresis.  |  Shlyakhovenko, V. and Samoylenko, O. 2022. Protein J. 41: 438-443. PMID: 35895218
  10. Evaluation of EDTA as the chelator in the biuret reagent.  |  Van Kley, H. and Claywell, CS. 1973. Clin Chem. 19: 621-3. PMID: 4196140
  11. Genetic toxicology of ethylenediaminetetraacetic acid (EDTA).  |  Heindorff, K., et al. 1983. Mutat Res. 115: 149-73. PMID: 6406880
  12. Separation and identification of some cephalosporins on impregnated TLC plates.  |  Bhushan, R. and Parshad, V. 1996. Biomed Chromatogr. 10: 258-60. PMID: 8879536
  13. Environmental fate of EDTA and DTPA.  |  Sillanpää, M. 1997. Rev Environ Contam Toxicol. 152: 85-111. PMID: 9297986

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

EDTA, Disodium Salt, Dihydrate, 100 g

sc-29092A
100 g
$48.00

EDTA, Disodium Salt, Dihydrate, 500 g

sc-29092
500 g
$98.00