Molecular structure of Edelfosine, CAS Number: 70641-51-9
Edelfosine (CAS 70641-51-9)
Alternate Names:
ET-18-OMe 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
CAS Number:
70641-51-9
Molecular Weight:
523.70
Molecular Formula:
C27H58NO6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Edelfosine (CAS 70641-51-9) References
- In vivo biodistribution of edelfosine-loaded lipid nanoparticles radiolabeled with Technetium-99 m: Comparison of administration routes in mice. | Lasa-Saracíbar, B., et al. 2022. Eur J Pharm Biopharm. 175: 1-6. PMID: 35462025
- Edelfosine reactivates latent HIV-1 reservoirs in myeloid cells through activation of NF-κB and AP1 pathway. | Rai, M., et al. 2022. Virology. 574: 57-64. PMID: 35926244
- Mutagenesis induced by protonation of single-stranded DNA is linked to glycolytic sugar metabolism. | Gelova, SP. and Chan, K. 2023. Mutat Res. 826: 111814. PMID: 36634476
- Antitumor activity of alkylphospholipid edelfosine in prostate cancer models and endoplasmic reticulum targeting. | Dakir, EH., et al. 2023. Biomed Pharmacother. 167: 115436. PMID: 37683591
- The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation. | Cui, SH., et al. 2024. Acta Pharmacol Sin. 45: 490-501. PMID: 37935896
- PIP2 regulating calcium signal modulates actin cytoskeleton-dependent cytoadherence and cytolytic capacity in the protozoan parasite Trichomonas vaginalis. | Chen, YJ., et al. 2023. PLoS Pathog. 19: e1011891. PMID: 38109416
- Targeting myeloma metabolism: How abnormal metabolism contributes to multiple myeloma progression and resistance to proteasome inhibitors. | Zhou, X., et al. 2024. Neoplasia. 50: 100974. PMID: 38364355
- Encapsulation of Nanoparticles with Statistical Copolymers with Different Surface Charges and Analysis of Their Interactions with Proteins and Cells. | Megahed, S., et al. 2024. Int J Mol Sci. 25: PMID: 38791579
- Glucocorticoids paradoxically promote steroid resistance in B cell acute lymphoblastic leukemia through CXCR4/PLC signaling. | Abdoul-Azize, S., et al. 2024. Nat Commun. 15: 4557. PMID: 38811530
- Activation of the cell wall integrity pathway negatively regulates TORC2-Ypk1/2 signaling through blocking eisosome disassembly in Saccharomyces cerevisiae. | Nomura, W. and Inoue, Y. 2024. Commun Biol. 7: 722. PMID: 38862688
Inhibitor of:
Gm266, INPP5B, ITPK1, LYPLA1, PAP-2a, PCYT2, PLC δ3, PLC ε2, PLC η1, PLC γ2, PLC 2, PLC-L, and PLCδ1.Activator of:
DGK-θ, EDG-2, PAF acetylhydrolase 2, PLC-L, and PLSCR3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Edelfosine, 5 mg | sc-507459 | 5 mg | $216.00 |