Molecular structure of (E,Z) 2-Propyl-2-pentenoic acid, CAS Number: 60218-41-9
(E,Z) 2-Propyl-2-pentenoic acid (CAS 60218-41-9)
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Alternate Names:
2-ene-VPA; 2-Propyl-2-pentenoate; 2-propylpenten-2-oic Acid
Application:
(E,Z) 2-Propyl-2-pentenoic acid is a valproic acid metabolite
CAS Number:
60218-41-9
Purity:
≥97%
Molecular Weight:
142.20
Molecular Formula:
C8H14O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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(E,Z) 2-Propyl-2-pentenoic Acid, exhibits a broad range of interactions with diverse proteins and enzymes, including fatty acid-binding proteins, acyl-CoA synthetases, and acyl-CoA dehydrogenases. Furthermore, it engages with various molecules such as phospholipids and lipids. These interactions are thought to underlie the biochemical and physiological effects attributed to 2-Pentenoic acid, 2-propyl-.
(E,Z) 2-Propyl-2-pentenoic acid (CAS 60218-41-9) References
- In vitro effects of valproate and valproate metabolites on mitochondrial oxidations. Relevance of CoA sequestration to the observed inhibitions. | Ponchaut, S., et al. 1992. Biochem Pharmacol. 43: 2435-42. PMID: 1610408
- Influence of CYP2C9 polymorphism on metabolism of valproate and its hepatotoxin metabolite in Iranian patients. | Amini-Shirazi, N., et al. 2010. Toxicol Mech Methods. 20: 452-7. PMID: 20602621
- Simultaneous Determination of Valproic Acid and Its Major Metabolites by UHPLC-MS/MS in Chinese Patients: Application to Therapeutic Drug Monitoring. | Zhao, M., et al. 2017. J Chromatogr Sci. 55: 436-444. PMID: 27993840
- Population pharmacokinetic modelling of valproic acid and its selected metabolites in acute VPA poisoning. | Jawień, W., et al. 2017. Pharmacol Rep. 69: 340-349. PMID: 28187395
- Liquid chromatography-tandem mass spectrometry method for simultaneous determination of valproic acid and its ene-metabolites in epilepsy patient plasma. | Lu, H., et al. 2016. J Pharm Anal. 6: 112-116. PMID: 29403970
- Cytotoxicity of unsaturated metabolites of valproic acid and protection by vitamins C and E in glutathione-depleted rat hepatocytes. | Jurima-Romet, M., et al. 1996. Toxicology. 112: 69-85. PMID: 8792850
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(E,Z) 2-Propyl-2-pentenoic acid, 10 mg | sc-211393 | 10 mg | $306.00 |