E-Selectin/CD62E/SELE Antibody (UZ6): sc-59766

E-Selectin Antibody (UZ6) is a rat monoclonal IgG2b antibody that detects E-Selectin in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). E-Selectin, also known as ELAM-1 or CD62E, is a crucial adhesion molecule expressed on the surface of endothelial cells, particularly when stimulated by cytokines during inflammatory responses. E-Selectin′s primary function is to mediate the adhesion of leukocytes to the vascular endothelium, facilitating their migration to sites of inflammation. This process is vital for the immune response, as E-Selectin allows immune cells to exit the bloodstream and reach areas of tissue damage or infection. E-Selectin′s ability to interact with specific carbohydrates on leukocytes underscores E-Selectin′s importance in regulating immune cell trafficking and maintaining homeostasis within the vascular system. Anti-E-Selectin antibody (UZ6) is an essential tool for researchers studying inflammation, immune responses, and related pathologies, providing insights into the mechanisms of leukocyte recruitment and the role of endothelial cells in these processes.

The preferred E-Selectin/CD62E/SELE antibody is E-Selectin/CD62E/SELE Antibody (D-7): sc-137054.