E-Selectin/CD62E/SELE Antibody (UZ5): sc-59765

E-Selectin Antibody (UZ5) is a rat monoclonal IgG2b antibody that detects E-Selectin in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). E-Selectin, also known as ELAM-1 or CD62E, is a crucial adhesion molecule expressed on the surface of endothelial cells, particularly in response to pro-inflammatory cytokines. E-Selectin′s primary function is to mediate the adhesion of leukocytes to the vascular endothelium during inflammatory responses, which is vital for the recruitment of immune cells to sites of injury or infection. Expression of E-Selectin is tightly regulated and occurs primarily in activated endothelial cells, making E-Selectin a key player in the inflammatory process. By facilitating the rolling and adhesion of leukocytes, E-Selectin plays an essential role in the immune response, influencing both the magnitude and duration of inflammation. Anti-E-Selectin antibody (UZ5) serves as an invaluable tool for researchers studying vascular biology and immune responses, providing insights into the mechanisms of cell adhesion and the pathophysiology of inflammatory diseases.

The preferred E-Selectin/CD62E/SELE antibody is E-Selectin/CD62E/SELE Antibody (D-7): sc-137054.