E-Selectin/CD62E/SELE Antibody (UZ4): sc-59764
- E-Selectin/CD62E/SELE Antibody (UZ4) is a rat monoclonal IgM, cited in 1 publications, provided at 100 µg/ml
- raised against LPS activated mlEND1of mouse oirgin
- recommended for detection of the minimal amino acid consensus sequence CXKKKL present in the lectin domain of E-Selectin of mouse, rat and human origin by WB, IP and FCM
- See E-Selectin/CD62E/SELE (D-7): sc-137054 for E-Selectin/CD62E/SELE antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for E-Selectin/CD62E/SELE Antibody (UZ4). This work is in progress.
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E-Selectin Antibody (UZ4) is a rat monoclonal IgM antibody that detects E-Selectin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). E-Selectin, also known as ELAM-1 or CD62E, plays a crucial role in the immune response by mediating the adhesion of leukocytes to the endothelium during inflammation. E-Selectin is primarily expressed on the surface of endothelial cells that have been stimulated by cytokines, which is vital for the recruitment of immune cells to sites of injury or infection. E-Selectin′s ability to interact with specific carbohydrates on leukocytes facilitates the rolling and adhesion processes necessary for leukocyte extravasation, making E-Selectin an essential component in the inflammatory response. Furthermore, E-Selectin′s expression is tightly regulated and can be influenced by various cytokines, highlighting E-Selectin′s importance in both normal immune function and pathological conditions such as chronic inflammation and autoimmune diseases. Anti-E-Selectin antibody (UZ4) is an invaluable tool for researchers studying these processes and the underlying mechanisms of immune cell trafficking.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
E-Selectin/CD62E/SELE Antibody (UZ4) | sc-59764 | 100 µg/ml | $322.00 |