Drimentine C (CAS 204398-92-5)

Drimentine C, identified by the CAS number 204398-92-5, is part of the drimentine group, which are known for their distinct bicyclic structures consisting of fused pyrrolidine and oxazoline rings. This particular compound exhibits a unique mechanism of action primarily focused on the inhibition of fungal efflux pumps. These efflux pumps are critical components in fungal cells, responsible for the expulsion of toxic substances and antifungal agents from the cell interior, thereby playing a key role in fungal resistance to environmental stresses and antifungal treatments. Drimentine C specifically targets and inhibits these pumps, thereby increasing the intracellular concentration of various substances that are otherwise expelled, which can lead to fungal cell toxicity and ultimately cell death. This action is of great interest in the field of mycology and pharmacological research, where Drimentine C is utilized to study the dynamics of fungal resistance mechanisms and to explore potential strategies for overcoming resistance. By inhibiting efflux pumps, researchers can better understand how these systems contribute to the resilience of fungal populations against hostile environments. This knowledge is crucial for developing innovative approaches to managing fungal growth and proliferation, particularly in agricultural settings where fungal resistance significantly impacts crop yield and quality.