Date published: 2026-5-18

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Drimenol (CAS 468-68-8)

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Datasheets
Alternate Names:
(−)-Drim-7-en-11-ol; (−)-Drimenol; Drim-7-en-11-ol
Application:
Drimenol is a sesquiterpene drimane that possesses antifungal activity
CAS Number:
468-68-8
Purity:
≥95%
Molecular Weight:
222.37
Molecular Formula:
C15H26O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Drimenol is a sesquiterpene alcohol derived from natural sources, particularly plants in the Drimys genus. It is widely studied in scientific research for its potential biological activities, including insecticidal, antimicrobial, and antifungal properties. The mechanism of action of drimenol is primarily attributed to its ability to interact with cellular membranes and proteins, disrupting their normal functions. This interaction can lead to increased membrane permeability, loss of cellular integrity, and inhibition of key enzymatic processes within target organisms. In research, drimenol is used to investigate its efficacy as a natural insect repellent and insecticide. Studies have demonstrated its effectiveness in repelling various insect species and disrupting their growth and development. This makes drimenol a valuable compound in the study of natural pest control methods, offering an alternative to synthetic chemicals. Additionally, drimenol′s antimicrobial properties are explored in microbiological studies. Researchers have found that drimenol can inhibit the growth of certain bacterial and fungal strains, making it a candidate for developing new antimicrobial agents. These studies help explain the compound′s mode of action and its potential applications in controlling microbial infections in agriculture and food preservation. Through these applications, drimenol contributes significantly to the understanding of natural product chemistry and its potential for developing sustainable solutions in pest management and antimicrobial strategies.


Drimenol (CAS 468-68-8) References

  1. Drimenol: A versatile synthon for compounds with trans-drimane skeleton.  |  Cortés, M., et al. 2011. Nat Prod Commun. 6: 477-90. PMID: 21560760
  2. Effect of drimenol and synthetic derivatives on growth and germination of Botrytis cinerea: Evaluation of possible mechanism of action.  |  Robles-Kelly, C., et al. 2017. Pestic Biochem Physiol. 141: 50-56. PMID: 28911740
  3. Biopesticide Activity from Drimanic Compounds to Control Tomato Pathogens.  |  Montenegro, I., et al. 2018. Molecules. 23: PMID: 30115841
  4. Antigrowth activity and induction of apoptosis in human melanoma cells by Drymis winteri forst extract and its active components.  |  Russo, A., et al. 2019. Chem Biol Interact. 305: 79-85. PMID: 30935903
  5. Broad-spectrum antifungal activities and mechanism of drimane sesquiterpenoids.  |  Edouarzin, E., et al. 2020. Microb Cell. 7: 146-159. PMID: 32548177
  6. Drimenol, isodrimeninol and polygodial isolated from Drimys winteri reduce monocyte adhesion to stimulated human endothelial cells.  |  Burgos, V., et al. 2020. Food Chem Toxicol. 146: 111775. PMID: 32987110
  7. Identification and Characterization of Bifunctional Drimenol Synthases of Marine Bacterial Origin.  |  Vo, NNQ., et al. 2022. ACS Chem Biol. 17: 1226-1238. PMID: 35446557
  8. Terpene Synthases in the Biosynthesis of Drimane-Type Sesquiterpenes across Diverse Organisms.  |  Chen, TH. and Lin, HC. 2023. Chembiochem. 24: e202300518. PMID: 37605310
  9. Siparuna guianensis Essential Oil Antitumoral Activity on Ehrlich Model and Its Effect on Oxidative Stress.  |  Viana Barbosa, LG., et al. 2023. Chem Biodivers. 20: e202301120. PMID: 37691004
  10. Bioconversion of drimenol into 3 beta-hydroxydrimanes by Aspergillus niger. Effect of culture additives.  |  Ramirez, HE., et al. 1993. J Nat Prod. 56: 762-4. PMID: 8326324

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Drimenol, 1 mg

sc-506432
1 mg
$235.00

Drimenol, 5 mg

sc-506432A
5 mg
$825.00