Date published: 2025-12-5

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Doxycycline hydrochloride (CAS 10592-13-9)

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Alternate Names:
Doxycycline hydrochloride is also known as Vibramycin hydrochloride.
Application:
Doxycycline hydrochloride is a tetracycline based anitbiotic and cell selection reagent
CAS Number:
10592-13-9
Molecular Weight:
480.90
Molecular Formula:
C22H24N2O8•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Doxycycline hydrochloride is an inhibitor of MMPa and is tetracycline based anitbiotic and cell selection reagent. Doxycycline Hydrochloride′s ability to bind to ribosomal subunits makes it useful for studying the effects of such interactions on gene expression and cellular metabolism. This has implications for understanding the regulation of protein production, the response of cells to various stressors, and the adaptation mechanisms of microorganisms to environmental changes. Doxycycline hydrochloride′s physicochemical properties, such as its solubility and stability in aqueous solutions, facilitate its use in various experimental setups. It can also find applications in environmental science, particularly in studies related to microbial ecology. Its impact on microbial communities can inform the development of strategies for managing bacterial populations.


Doxycycline hydrochloride (CAS 10592-13-9) References

  1. Antibacterial activity of doxycycline-loaded nanoparticles.  |  Misra, R. and Sahoo, SK. 2012. Methods Enzymol. 509: 61-85. PMID: 22568901
  2. Vesicular powder as carrier for doxycycline hydrochloride and metronidazole combination therapy.  |  Gad, HA., et al. 2014. Pharm Dev Technol. 19: 755-68. PMID: 23981239
  3. Engineering of polymer-surfactant nanoparticles of doxycycline hydrochloride for ocular drug delivery.  |  Pokharkar, V., et al. 2015. Drug Deliv. 22: 955-68. PMID: 24601827
  4. Genotoxicity evaluation of asymmetric lipid polymer hybrid nanoparticles of doxycycline hydrochloride following intravenous administration.  |  Soni, MP., et al. 2013. Drug Deliv Transl Res. 3: 421-7. PMID: 25788350
  5. Preparation, characterization and pharmacokinetics of doxycycline hydrochloride and florfenicol polyvinylpyrroliddone microparticle entrapped with hydroxypropyl-β-cyclodextrin inclusion complexes suspension.  |  Li, X., et al. 2016. Colloids Surf B Biointerfaces. 141: 634-642. PMID: 26918512
  6. Subcutaneously Administered Ultrafine PLGA Nanoparticles Containing Doxycycline Hydrochloride Target Lymphatic Filarial Parasites.  |  Singh, Y., et al. 2016. Mol Pharm. 13: 2084-94. PMID: 27144397
  7. Facile synthesis of Cu(II) impregnated biochar with enhanced adsorption activity for the removal of doxycycline hydrochloride from water.  |  Liu, S., et al. 2017. Sci Total Environ. 592: 546-553. PMID: 28318694
  8. Brain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral, biochemical, neurochemical and histological alterations in mice.  |  Yadav, M., et al. 2017. Drug Deliv. 24: 1429-1440. PMID: 28942680
  9. Lignin xanthate resin-bentonite clay composite as a highly effective and low-cost adsorbent for the removal of doxycycline hydrochloride antibiotic and mercury ions in water.  |  Kong, Y., et al. 2019. J Hazard Mater. 368: 33-41. PMID: 30665106
  10. Surface-enhanced Raman spectroscopy method for classification of doxycycline hydrochloride and tylosin in duck meat using gold nanoparticles.  |  Wang, T., et al. 2021. Poult Sci. 100: 101165. PMID: 33975036
  11. In-situ fabrication of ionic liquids/MIL-68(In)-NH2 photocatalyst for improving visible-light photocatalytic degradation of doxycycline hydrochloride.  |  Li, D., et al. 2022. Chemosphere. 292: 133461. PMID: 34974040
  12. Adsorptive decontamination of doxycycline hydrochloride via Prosopis juliflora activated carbon: Parameter optimization and disposal study.  |  Kaur, G., et al. 2022. Water Environ Res. 94: e10687. PMID: 35165966
  13. Towards BioMnOx-mediated intra/extracellular electron shuttling for doxycycline hydrochloride metabolism in Bacillus thuringiensis.  |  Zhou, M., et al. 2022. J Environ Manage. 320: 115891. PMID: 36056494
  14. Doxycycline Hydrochloride Regulates Cytoskeletal Rearrangement and Epithelial-To-Mesenchymal Transition in Malignant Rhabdoid Tumour of the Kidney.  |  Zhanghuang, C., et al. 2022. Biomed Res Int. 2022: 2760744. PMID: 36408277
  15. Poly (trimethylene carbonate)/doxycycline hydrochloride films in the treatment of Achilles tendon defect in rats.  |  Zhang, J., et al. 2023. Front Bioeng Biotechnol. 11: 1135248. PMID: 36911187

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Doxycycline hydrochloride, 10 g

sc-337691
10 g
$112.00

Doxycycline hydrochloride, 25 g

sc-337691A
25 g
$210.00

Doxycycline hydrochloride, 100 g

sc-337691B
100 g
$653.00