Date published: 2025-10-15

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DOTAP Transfection Reagent (CAS 144189-73-1)

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Alternate Names:
DOTAP Transfection Reagent is also known as DOTAP methosulfate.
Application:
DOTAP Transfection Reagent is a cationic lipid formulation used for transfection of DNA, RNA, and YAC.
CAS Number:
144189-73-1
Molecular Weight:
774.19
Molecular Formula:
C42H80NO4•SO4CH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DOTAP Transfection Reagent is a liposomal formulation of the cationic lipid DOTAP. DOTAP Transfection Reagent is used not only for DNA and RNA transfection, but yeast artificial chromosomes (YAC) as well, with or without serum. This transfection via DOTAP Transfection Reagent is between eukaryotic cells in iehter transient or stable gene expression. DOTAP Transfection Reagent is also suitable for other negatively charged molecules, including oligonucleotidees and glutamic acid.


DOTAP Transfection Reagent (CAS 144189-73-1) References

  1. Aging impairs IFN regulatory factor 7 up-regulation in plasmacytoid dendritic cells during TLR9 activation.  |  Stout-Delgado, HW., et al. 2008. J Immunol. 181: 6747-56. PMID: 18981092
  2. Borrelia burgdorferi RNA induces type I and III interferons via Toll-like receptor 7 and contributes to production of NF-κB-dependent cytokines.  |  Love, AC., et al. 2014. Infect Immun. 82: 2405-16. PMID: 24664510
  3. Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.  |  Sork, H., et al. 2016. Mol Ther Nucleic Acids. 5: e290. PMID: 27111416

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DOTAP Transfection Reagent, 400 µl

sc-362166
400 µl
$178.00