Date published: 2025-12-15

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Dodin (CAS 2439-10-3)

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Alternate Names:
Dodine
Application:
Dodin is an agricultural fungicide
CAS Number:
2439-10-3
Molecular Weight:
287.44
Molecular Formula:
C13H29N3•C2H4O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dodine is a white crystalline solid primarily employed as an agricultural fungicide. It is an 1-dodecylguanidine acetate, which is a salt formed by the reaction of equal amounts of 1-dodecylguanidine and acetic acid. It serves as a fungicide for the control of black spot and foliar diseases in various fruits like apples, pears, peaches, nectarines, and strawberries. In addition to its fungicidal properties, it acts as an antibacterial and antifungal agent in the field of agriculture. Notably, 1-dodecylguanidine acetate is categorized as an aliphatic nitrogen antifungal agent, owing to its composition featuring a 1-dodecylguanidine(1+) moiety and an acetate salt.


Dodin (CAS 2439-10-3) References

  1. Comment on 'Determination of the critical micelle concentration of dodecylguanidine monoacetate (dodine)'.  |  Inoue, T., et al. 2007. J Colloid Interface Sci. 314: 334-6. PMID: 17617418
  2. Determination of dodine in fruit samples by liquid chromatography electrospray ionization-tandem mass spectrometry.  |  Le Grand, R., et al. 2011. J AOAC Int. 94: 300-6. PMID: 21391507
  3. Evaluation of dodine, fluopyram and penthiopyrad for the management of leaf spot and powdery mildew of tart cherry, and fungicide sensitivity screening of Michigan populations of Blumeriella jaapii.  |  Proffer, TJ., et al. 2013. Pest Manag Sci. 69: 747-54. PMID: 23175430
  4. Dodine as a protein denaturant: the best of two worlds?  |  Gelman, H., et al. 2013. J Phys Chem B. 117: 13090-7. PMID: 23906507
  5. Dodine as a transparent protein denaturant for circular dichroism and infrared studies.  |  Guin, D., et al. 2016. Protein Sci. 25: 1061-8. PMID: 26941080
  6. Molecular dynamics approach to understand the denaturing effect of a millimolar concentration of dodine on a λ-repressor and counteraction by trehalose.  |  Borgohain, G., et al. 2017. Phys Chem Chem Phys. 19: 13160-13171. PMID: 28489086
  7. Interactive Effects of Dodine and the DMI Fungicide Fenarimol in the Control of Apple Scab.  |  Köller, W. and Wilcox, WF. 2000. Plant Dis. 84: 863-870. PMID: 30832140
  8. Does Fungicide 'Dodine' Unfold Protein like Kosmo-Chaotropic Agent?  |  Biswas, B. and Singh, PC. 2019. J Phys Chem B. 123: 8240-8246. PMID: 31487177
  9. The conformational stability of terminal helices of λ-repressor protein in aqueous dodine and choline-O-sulfate solutions.  |  Paul, S. and Paul, S. 2020. Int J Biol Macromol. 154: 1332-1346. PMID: 31783075
  10. An investigation of histopathological changes and bioaccumulation in tissues of rainbow trout (Oncorhynchus mykiss) after exposure to dodine.  |  Büyüksoylu, S., et al. 2022. Drug Chem Toxicol. 45: 537-547. PMID: 32102573
  11. The fungicide dodine primarily inhibits mitochondrial respiration in Ustilago maydis, but also affects plasma membrane integrity and endocytosis, which is not found in Zymoseptoria tritici.  |  Schuster, M. and Steinberg, G. 2020. Fungal Genet Biol. 142: 103414. PMID: 32474016
  12. Detecting Pesticide Dodine by Displacement of Fluorescent Acridine from Cucurbit[10]uril Macrocycle.  |  Xu, WT., et al. 2021. J Agric Food Chem. 69: 584-591. PMID: 33377764
  13. Spectroscopic and Simulation Studies of the Sequence-Dependent DNA Destabilization by a Fungicide.  |  Sarkar, S. and Chandra Singh, P. 2021. ACS Omega. 6: 14371-14378. PMID: 34124459
  14. Modification of the existing maximum residue levels for dodine in citrus fruits.  |  , ., et al. 2021. EFSA J. 19: e06950. PMID: 34853616
  15. Supramolecular Room Temperature Phosphorescent Materials Based on Cucurbit[8]uril for Dual Detection of Dodine.  |  Zhang, W., et al. 2022. ACS Appl Mater Interfaces. 14: 51429-51437. PMID: 36342086

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dodin, 250 mg

sc-227969
250 mg
$42.00

Dodin, 5 g

sc-227969A
5 g
$531.00