Molecular structure of Docetaxel-d5, CAS Number: 114977-28-5 (unlabeled)
Docetaxel-d5 (CAS 114977-28-5 (unlabeled))
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Application:
Docetaxel-d5 is an antineoplastic
CAS Number:
114977-28-5 (unlabeled)
Molecular Weight:
812.91
Molecular Formula:
C43H48D5NO14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
An antineoplastic. An antimitotic agent that promotes the assembly of microtublules and inhibits their depolymerization to free tubulin.
Docetaxel-d5 (CAS 114977-28-5 (unlabeled)) References
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- The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis. | Follet, J., et al. 2012. Br J Cancer. 106: 685-92. PMID: 22294184
- Stable isotope method to measure drug release from nanomedicines. | Skoczen, S., et al. 2015. J Control Release. 220: 169-174. PMID: 26596375
- Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel. | Grudén, S., et al. 2017. Eur J Pharm Biopharm. 114: 186-193. PMID: 28161551
- Determination of docetaxel in dried blood spots by LC-MS/MS: Method development, validation and clinical application. | Raymundo, S., et al. 2018. J Pharm Biomed Anal. 157: 84-91. PMID: 29775811
- A new method for the determination of total and released docetaxel from docetaxel-entrapped core-crosslinked polymeric micelles (CriPec®) by LC-MS/MS and its clinical application in plasma and tissues in patients with various tumours. | Braal, CL., et al. 2018. J Pharm Biomed Anal. 161: 168-174. PMID: 30165333
- Technological advancement in dry blood matrix microsampling and its clinical relevance in quantitative drug analysis. | Shitole, V., et al. 2020. Bioanalysis. 12: 1483-1501. PMID: 33006487
- A comparative biodistribution study of polymeric and lipid-based nanoparticles. | Åslund, AKO., et al. 2022. Drug Deliv Transl Res. 12: 2114-2131. PMID: 35426570
- Phase 1 trial of bemcentinib (BGB324), a first-in-class, selective AXL inhibitor, with docetaxel in patients with previously treated advanced non-small cell lung cancer. | Bhalla, S., et al. 2023. Lung Cancer. 182: 107291. PMID: 37423058
- Phase I and pharmacokinetic study of Taxotere (RP 56976; NSC 628503) given as a short intravenous infusion. | Extra, JM., et al. 1993. Cancer Res. 53: 1037-42. PMID: 8094996
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Docetaxel-d5, 500 µg | sc-218257 | 500 µg | $507.00 |