Molecular structure of DNA-PK Inhibitor V, CAS Number: 404009-46-7
DNA-PK Inhibitor V (CAS 404009-46-7)
Alternate Names:
AMA37; ArylMorpholine Analog 37; 1-(2-Hydroxy-4-morpholin-4-yl-phenyl)-phenyl-methanone
Application:
DNA-PK Inhibitor V is a morpholino-benzophenone ATP-competitive inhibitor
CAS Number:
404009-46-7
Molecular Weight:
283.3
Molecular Formula:
C17H17NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
DNA-PK Inhibitor V is a morpholino-benzophenone compound. Potent, selective and ATP-competitive inhibitor of DNA-PK (IC50 = 270 nM). Inhibits PI 3-K catalytic subunit p110-isozymes at higher concentrations (IC50 = 32 μM, 3.7 μM, 22 μM and ~ 100μM for α, β, δ and γ, respectively) and weakly inhibits a panel of several other kinases, including, ATM, ATR, CK2, GRK2, mTOR, PI 3KC2α, PI 3KC2β, PI 3KC2γ and PI 4Kβ, even at concentrations as high as 50μM.
Inhibitor of:
DNA-PK, and PI 3-kinase p110 beta.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DNA-PK Inhibitor V, 1 mg | sc-203929 | 1 mg | $140.00 | |||
DNA-PK Inhibitor V, 5 mg | sc-203929A | 5 mg | $510.00 |