Molecular structure of DL-Propargylglycine (hydrochloride), CAS Number: 16900-57-5
DL-Propargylglycine (hydrochloride) (CAS 16900-57-5)
Alternate Names:
2-amino-4-pentynoic acid, monohydrochloride
Application:
DL-Propargylglycine (hydrochloride) is an irreversible inhibitor of the H2S synthesizing enzyme CSE
CAS Number:
16900-57-5
Purity:
≥95%
Molecular Weight:
149.6
Molecular Formula:
C5H7NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
DL-Propargylglycine (hydrochloride) is an irreversible inhibitor of cystathionine-γ-lyase (CSE), which is a H2S synthesizing enzyme. Studies show that DL-Propargylglycine (hydrochloride) effects glycogenolysis in rat hepatocytes. This acetylenic amino acid can also inhibit alanine aminotransferase in hepatocytes and to a lesser extent inhbits aspartate aminotransferase. Alternate studies on Lemna paucicostata Hegelm show that DL-Propargylglycine (hydrochloride) inhibits methionine biosynthesis, causes growth inhibition, and morphological changes.
DL-Propargylglycine (hydrochloride) (CAS 16900-57-5) References
- Effects of mushroom toxins on glycogenolysis; comparison of toxicity of phalloidin, alpha-amanitin and DL-propargylglycine in isolated rat hepatocytes. | Kawaji, A., et al. 1992. J Pharmacobiodyn. 15: 107-12. PMID: 1320679
- Methionine biosynthesis in lemna: inhibitor studies. | Datko, AH. and Mudd, SH. 1982. Plant Physiol. 69: 1070-6. PMID: 16662347
- Selective inhibition of alanine aminotransferase and aspartate aminotransferase in rat hepatocytes. | Cornell, NW., et al. 1984. Biochem J. 220: 707-16. PMID: 6466297
Inhibitor of:
CTH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DL-Propargylglycine (hydrochloride), 1 mg | sc-221558 | 1 mg | $24.00 | |||
DL-Propargylglycine (hydrochloride), 5 mg | sc-221558A | 5 mg | $110.00 | |||
DL-Propargylglycine (hydrochloride), 10 mg | sc-221558B | 10 mg | $147.00 | |||
DL-Propargylglycine (hydrochloride), 50 mg | sc-221558C | 50 mg | $643.00 |