Date published: 2026-4-5

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DL-Propargylglycine (CAS 64165-64-6)

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Alternate Names:
DL-Propargyl-Gly-OH
CAS Number:
64165-64-6
Molecular Weight:
113.1
Molecular Formula:
C5H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-Propargylglycine is a versatile compound utilized in biochemical and chemical synthesis research. Its presence in studies often relates to the inhibition of enzymes, such as cystathionine gamma-lyase, which are involved in the metabolism of amino acids like cysteine. The propargyl moiety of DL-Propargylglycine serves as a key functional group in the design of enzyme inhibitors due to its ability to interact with the active sites of enzymes. Additionally, this compound is used in the field of organic synthesis, where it can be employed as a non-natural amino acid in the preparation of peptidomimetics and other modified peptides. Its alkyne group is particularly useful in click chemistry reactions, which are widely applied in the development of new materials and bioconjugation techniques. Researchers also investigate the incorporation of DL-Propargylglycine into proteins to study protein function and to produce proteins with altered properties for industrial applications.


DL-Propargylglycine (CAS 64165-64-6) References

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  2. Propargylglycine inhibits hypotaurine/taurine synthesis and elevates cystathionine and homocysteine concentrations in primary mouse hepatocytes.  |  Jurkowska, H., et al. 2015. Amino Acids. 47: 1215-23. PMID: 25772816
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  14. NaHS restores the vascular alterations in the renin-angiotensin system induced by hyperglycemia in rats.  |  Silva-Velasco, DL., et al. 2023. Peptides. 164: 171001. PMID: 36990388
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-Propargylglycine, 1 g

sc-294408
1 g
$172.00

DL-Propargylglycine, 5 g

sc-294408A
5 g
$692.00