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DL-Methionine (CAS 59-51-8)

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Alternate Names:
(±)-2-Amino-4-(methylmercapto)butyric acid
Application:
DL-Methionine is an essential nonpolar amino acid with oxidative stress defense properties
CAS Number:
59-51-8
Molecular Weight:
149.21
Molecular Formula:
C5H11NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-Methionine is an amino acid that is used in biochemistry and nutrition research. It is a racemic mixture of the D- and L- forms of methionine, which are mirror images of each other. In research involving protein synthesis, DL-Methionine is used to study the incorporation of sulfur-containing amino acids into peptides and proteins. It is also a focal point in studies on metabolism, as methionine is a critical precursor for various metabolic pathways, including the synthesis of S-adenosylmethionine, an important methyl donor. Furthermore, researchers use DL-Methionine to examine its influence on growth and oxidative stress mechanisms in cell cultures.


DL-Methionine (CAS 59-51-8) References

  1. Synthesis of DL-methionine.  |  PIERSON, E., et al. 1948. J Am Chem Soc. 70: 1450. PMID: 18915761
  2. Synthesis of dl-methionine.  |  LIVAK, JE. and BRITTON, EC. 1945. J Am Chem Soc. 67: 2218-20. PMID: 21005691
  3. Characterization of the segmental transport mechanisms of DL-methionine hydroxy analogue along the intestinal tract of rainbow trout with an additional comparison to DL-methionine.  |  Pham Thi Ha To, V., et al. 2020. Comp Biochem Physiol A Mol Integr Physiol. 249: 110776. PMID: 32712085
  4. Effects of Varying Dietary DL-Methionine Levels on Productive and Reproductive Performance, Egg Quality, and Blood Biochemical Parameters of Quail Breeders.  |  Reda, FM., et al. 2020. Animals (Basel). 10: PMID: 33050290
  5. Bioavailability of the calcium salt of dl-methionine hydroxy analog compared with dl-methionine for nitrogen retention and the preference of nursery pigs for diets based on the 2 forms of methionine.  |  Wang, MQ., et al. 2020. J Anim Sci. 98: PMID: 33111146
  6. Combining DL-Methionine and Bacillus thuringiensis Subspecies israelensis: Prospects for a Mosquito Larvicide.  |  Richardson, EA., et al. 2020. Insects. 11: PMID: 33322550
  7. Novel effective mosquito larvicide DL-methionine: Lack of toxicity to non-target aquatic organisms.  |  Weeks, ENI., et al. 2021. Ecotoxicol Environ Saf. 213: 112013. PMID: 33601173
  8. Bioavailability of the dl-methionine and the calcium salt of dl-methionine hydroxy analog compared with l-methionine for nitrogen retention in starter pigs.  |  Zhou, H., et al. 2021. J Anim Sci. 99: PMID: 33956968
  9. DL-methionine and DL-methionyl-DL-methionine increase intestinal development and activate Wnt/β-catenin signaling activity in domestic pigeons (Columba livia).  |  Zhong, C., et al. 2022. Poult Sci. 101: 101644. PMID: 34986451
  10. Evaluating growth response of broiler chickens fed diets supplemented with synthetic DL-methionine or DL-hydroxy methionine: a meta-analysis.  |  Uddin, ME., et al. 2022. Poult Sci. 101: 101762. PMID: 35278757
  11. dl-Methionine supplementation in a low-fishmeal diet affects the TOR/S6K pathway by stimulating ASCT2 amino acid transporter and insulin-like growth factor-I in the dorsal muscle of juvenile cobia (Rachycentron canadum) - CORRIGENDUM.  |  He, Y., et al. 2022. Br J Nutr. 127: 150. PMID: 35393926
  12. Methionine deficiency facilitates antitumour immunity by altering m6A methylation of immune checkpoint transcripts.  |  Li, T., et al. 2023. Gut. 72: 501-511. PMID: 35803704
  13. Dietary methionine starvation impairs acute myeloid leukemia progression.  |  Cunningham, A., et al. 2022. Blood. 140: 2037-2052. PMID: 35984907
  14. Increased Sulphur Amino Acids Consumption as OH-Methionine or DL-Methionine Improves Growth Performance and Carcass Traits of Growing-Finishing Pigs Fed under Hot Conditions.  |  da Silva, CA., et al. 2022. Animals (Basel). 12: PMID: 36077880
  15. Comparative metabolism of L-methionine, DL-methionine and DL-2-hydroxy 4-methylthiobutanoic acid by broiler chicks.  |  Saunderson, CL. 1985. Br J Nutr. 54: 621-33. PMID: 3939689

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-Methionine, 100 g

sc-397777
100 g
$44.00