Date published: 2026-3-6

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DL-Lysine-4,4,5,5-d4 dihydrochloride (CAS 284664-88-6)

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Application:
DL-Lysine-4,4,5,5-d4 dihydrochloride is a labeled amino acid derivative
CAS Number:
284664-88-6
Molecular Weight:
223.13
Molecular Formula:
C6H10D4N2O2 2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-Lysine-4,4,5,5-d4 dihydrochloride is a preparation of a deuterated Lysine (sc-207804). This derivative is deuterated at the 4 and 5 positions of the Lysine side-chain, and is a racemate of the two possible Lysine enantiomers. DL-Lysine-4,4,5,5-d4 has been described as a useful mass spectrometry reference against the natural amino acid for studying histone acetylation dynamics and other post-translational modifications and for identifying and quantifying protein methylation sites.


DL-Lysine-4,4,5,5-d4 dihydrochloride (CAS 284664-88-6) References

  1. Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.  |  Ong, SE., et al. 2004. Nat Methods. 1: 119-26. PMID: 15782174
  2. Histone H4 acetylation dynamics determined by stable isotope labeling with amino acids in cell culture and mass spectrometry.  |  Su, X., et al. 2007. Anal Biochem. 363: 22-34. PMID: 17286952
  3. Quantitative profiling of histone post-translational modifications by stable isotope labeling.  |  Knapp, AR., et al. 2007. Methods. 41: 312-9. PMID: 17309842
  4. Automated precolumn derivatization system for analyzing physiological amino acids by liquid chromatography/mass spectrometry.  |  Shimbo, K., et al. 2010. Biomed Chromatogr. 24: 683-91. PMID: 19830681

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-Lysine-4,4,5,5-d4 dihydrochloride, 1 g

sc-234825
1 g
$1095.00