Date published: 2026-2-9

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DL-Lactonitrile (CAS 78-97-7)

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Alternate Names:
2-Hydroxypropionitrile; Acetaldehyde cyanohydrin
CAS Number:
78-97-7
Purity:
≥97%
Molecular Weight:
71.08
Molecular Formula:
C3H5NO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DL-Lactonitrile is a useful compoud for the synthesis of lactamides through the fed-batch method, using the nitrile hydratase of Rhodococcus pyridinivorans NIT-36. It is an organic compound containing a hydroxyl group in the alpha position. DL-Lactonitrile finds applications as a reactant in organic synthesis and as a reagent for the production of metal hydroxides. The synthesis of DL-Lactonitrile can be achieved by reacting phosphorus pentoxide, hydrogen gas, and ammonia. The hydroxyl groups can form acids upon interaction with metal hydroxides and inorganic acids like phosphoric acid. The mechanism of this process has been studied using various techniques, including X-ray diffraction. Furthermore, DL-Lactonitrile plays a role in facilitating cross-linking reactions between amide groups through the formation of amide bonds, as well as in inducing enzyme activity.


DL-Lactonitrile (CAS 78-97-7) References

  1. The industrial potential of microbial nitrile biochemistry.  |  Wyatt, JM. and Linton, EA. 1988. Ciba Found Symp. 140: 32-48. PMID: 3073061
  2. Hydroxynitrile lyase defends Arabidopsis against Tetranychus urticae.  |  Arnaiz, A., et al. 2022. Plant Physiol. 189: 2244-2258. PMID: 35474139

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

DL-Lactonitrile, 25 ml

sc-234818
25 ml
$70.00